Gene Therapy Updates for Inherited Retinal Dystrophies

M Lu, D Milad, CX Qian - Canadian Eye Care Today, 2024 - canadianeyecaretoday.com
Inherited retinal dystrophies (IRDs) encompass a group of genetically diverse disorders,
each uniquely influencing distinct retinal cell pathways and retinal areas. IRDs currently …

[PDF][PDF] Gene Therapy Updates for Inherited Retinal Dystrophies

CX Qian - researchgate.net
Inherited retinal dystrophies (IRDs) encompass a group of genetically diverse disorders,
each uniquely influencing distinct retinal cell pathways and retinal areas. IRDs currently …

[HTML][HTML] Advances and Challenges in Gene Therapy for Inherited Retinal Dystrophies: A Comprehensive Review

R Jain, S Daigavane - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Inherited retinal dystrophies (IRDs) are a diverse group of genetic disorders leading to
progressive vision loss due to the degeneration of retinal photoreceptors. Gene therapy has …

[引用][C] Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond

ASBDC Parameswarappa, B Takkar, RNSJS Mandal… - 2023 - europepmc.org
This comprehensive review provides a thorough examination of inherited retinal diseases
(IRDs), encompassing their classification, genetic underpinnings, and the promising …

Genes and gene therapy in inherited retinal disease

A Shughoury, TA Ciulla, B Bakall… - International …, 2021 - journals.lww.com
Inherited retinal diseases (IRDs) are a leading cause of legal blindness in children and
working-age adults, accounting for up to 20% of all blind individuals aged 16 to 64. 1 …

[HTML][HTML] Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond

AS Brar, DC Parameswarappa, B Takkar… - Ophthalmology and …, 2024 - Springer
This comprehensive review provides a thorough examination of inherited retinal diseases
(IRDs), encompassing their classification, genetic underpinnings, and the promising …

Inherited retinal dystrophies

BR Yerxa - Handbook of Basic and Clinical Ocular Pharmacology …, 2022 - Elsevier
The inherited retinal dystrophies (IRDs) are comprised of a wide variety of genetically-
driven, blinding diseases in which each genetic variant represents a very small population …

[HTML][HTML] Gene Therapy: The New Frontier for Inherited Retinal Disease

C Kay - Retina Specialist, 2017 - retina-specialist.com
In the past 15 years, research in the field of retinal gene therapy has exploded. While no
treatments have yet been approved for any inherited retinal dystrophies, clinical trials …

Gene therapy for inherited retinal disorders: update on clinical trials

S Michalakis, M Gerhardt, G Rudolph… - Klinische …, 2021 - thieme-connect.com
Within the last decade, continuous advances in molecular biological techniques have made
it possible to develop causative therapies for inherited retinal disorders (IRDs). Some of the …

[HTML][HTML] CLINICAL TRIAL DOWNLOAD: Update on Advances Toward Therapeutics in Inherited Retinal Dystrophies

Y Modi, PY Zhao, T Jayasundera - retinalphysician.com
About 10 years ago, an ophthalmology resident described inherited retinal dystrophies
(IRDs) to me as a “sleepy field with minimal interventions.” While potentially true at that time …