Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models

J Gil-Mohapel, F Boehme, L Kainer, BR Christie - Brain research reviews, 2010 - Elsevier
Prenatal ethanol exposure is invariably detrimental to the developing central nervous
system and the hippocampus is particularly sensitive to the teratogenic effects of ethanol …

Altered adult hippocampal neuronal maturation in a rat model of fetal alcohol syndrome

J Gil-Mohapel, F Boehme, A Patten, A Cox, L Kainer… - Brain research, 2011 - Elsevier
Exposure to ethanol during pregnancy can be devastating to the developing nervous
system, leading to significant central nervous system dysfunction. The hippocampus, one of …

Effects of prenatal alcohol exposure on the hippocampus: spatial behavior, electrophysiology, and neuroanatomy

RF Berman, JH Hannigan - Hippocampus, 2000 - Wiley Online Library
Prenatal exposure to alcohol can result in fetal alcohol syndrome (FAS), characterized by
growth retardation, facial dysmorphologies, and a host of neurobehavioral impairments …

Critical periods for ethanol-induced cell loss in the hippocampal formation

TD Tran, SJ Kelly - Neurotoxicology and teratology, 2003 - Elsevier
Rodent models of fetal alcohol syndrome (FAS) have revealed discrepant findings in
ethanol's (EtOH) ability to alter the survival of principal neurons within hippocampal areas …

Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure

AY Klintsova, JL Helfer, LH Calizo… - Alcoholism: Clinical …, 2007 - Wiley Online Library
Background: Prenatal alcohol exposure can cause damage to the developing fetus with
outcomes including growth deficiency, facial dysmorphology, brain damage, and cognitive …

Moderate fetal alcohol exposure impairs the neurogenic response to an enriched environment in adult mice

IY Choi, AM Allan… - Alcoholism: Clinical and …, 2005 - Wiley Online Library
Background: Prenatal ethanol exposure results in a spectrum of cognitive and behavioral
deficits and affects an estimated thirteen percent of children born in the United States. The …

Single alcohol exposure in early life damages hippocampal stem/progenitor cells and reduces adult neurogenesis

A Ieraci, DG Herrera - Neurobiology of disease, 2007 - Elsevier
Alcohol exposure during pregnancy may cause fetal alcohol syndrome (FAS), characterized
by impaired cognitive functions. Neurogenesis occurs in the adult hippocampus and is …

Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations

CJ Fontaine, AR Patten, HM Sickmann, JL Helfer… - Neuroscience & …, 2016 - Elsevier
The consumption of alcohol during gestation is detrimental to the developing central
nervous system (CNS). The severity of structural and functional brain alterations associated …

Prenatal exposure to moderate levels of ethanol can have long‐lasting effects on hippocampal synaptic plasticity in adult offspring

RJ Sutherland, RJ McDonald, DD Savage - Hippocampus, 1997 - Wiley Online Library
Prenatal ethanol exposure has been associated with long‐lasting intellectual impairments in
children. Previous studies using animal models of fetal ethanol exposure suggest that these …

Prenatal exposure to ethanol decreases physiological plasticity in the hippocampus of the adult rat

HS Swartzwelder, KL Farr, WA Wilson, DD Savage - Alcohol, 1988 - Elsevier
Prenatal exposure to ethanol has been associated with birth defects ranging in severity from
physical dysmorphias and profound mental retardation to more subtle compromises of …