Rationale: Annual computed tomography (CT) is now widely recommended for lung cancer
screening in the United States, although concerns remain regarding the potential harms …

Context Smoking is a major risk factor for both cancer and chronic obstructive pulmonary
disease (COPD). Computed tomography (CT)–based lung cancer screening may provide an …

Rationale: Although epidemiological studies consistently show that chronic obstructive
pulmonary disease is associated with an increased risk of lung cancer, debate exists as to …

Lung cancer and chronic obstructive pulmonary disease (COPD) are two intimately related
diseases, with great impact on public health. Annual screening using low-dose computed …

Background Lung cancer is a leading cause of death and hospitalization for patients with
COPD. A detailed understanding of which clinical features of COPD increase risk is needed …

Background COPD is a major cause of morbidity and mortality in populations eligible for
lung cancer screening. We investigated the role of spirometry in a community-based lung …

Rationale: Lung cancer (LC) screening using low-dose chest computed tomography is now
recommended in several guidelines using the National Lung Screening Trial (NLST) entry …

Rationale: Individuals eligible for lung cancer screening (LCS) by low-dose computed
tomography (LDCT) are also at risk of chronic obstructive pulmonary disease (COPD) due to …

Background Lung cancer screening may provide a favorable opportunity for a spirometry
examination, to diagnose participants with undiagnosed lung function impairments, or to …

Background To study the relationship between emphysema, airflow obstruction, and lung
cancer in a high-risk population, we performed quantitative analysis of screening computed …