Stimulator-of-interferon gene (STING) is a vital element of the innate immune system against
DNA viruses. Optimal activation of STING is crucial for maintaining immune homeostasis …

Abstract The Stimulator of Interferon Genes (STING) has a crucial role in mediating the
immune response against cytosolic double-stranded DNA (dsDNA) and its activation is …

Background Stimulation of IFN genes (STING) is central to the production of interferon and
proinflammatory cytokines in response to microbial DNA or self-DNA in the cytosol. The …

Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-
sensing signaling pathway, which recognizes genomic DNA from invading pathogens to …

Stimulator of interferon genes (STING) is an endoplasmic-reticulum resident protein, playing
essential roles in immune responses against microbial infections. However, over-activation …

Herpes simplex virus (HSV) has persisted within human populations due to its ability to
establish both lytic and latent infection. Given this, human hosts have evolved numerous …

ABSTRACT The STimulator of INterferon Genes (STING) constitutes a major DNA-sensing
pathway that restricts HSV-1 infection in different models by activating type I interferon and …

STING (also known as MITA) is a central component in innate immunity against DNA virus.
In this issue of Immunity, Wang et al.(2014) demonstrate that K27-linked polyubiquitination …

STING is essential for control of infections and for tumor immunosurveillance, but it can also
drive pathological inflammation. STING resides on the endoplasmic reticulum (ER) and …

Stimulator of interferon genes (STING) mediates the innate immune response against
damaged endogenous double‐strand DNA and exogenous virus infection. The location of …