[HTML][HTML] Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

BS Penman, A Moffett, O Chazara, S Gupta, P Parham - Immunogenetics, 2016 - Springer
Killer-cell immunoglobulin-like receptors (KIRs) are encoded by one of the most polymorphic
families in the human genome. KIRs are expressed on natural killer (NK) cells, which have …

Human and rhesus macaque KIR haplotypes defined by their transcriptomes

J Bruijnesteijn, MKH van der Wiel… - The Journal of …, 2018 - journals.aai.org
The killer-cell Ig-like receptors (KIRs) play a central role in the immune recognition in
infection, pregnancy, and transplantation through their interactions with MHC class I …

The extreme plasticity of killer cell Ig‐like receptor (KIR) haplotypes differentiates rhesus macaques from humans

JH Blokhuis, MK van der Wiel… - European Journal of …, 2011 - Wiley Online Library
NK cells are essential in shaping immune responses and play an important role during
pregnancy and in controlling infections. Killer cell immunoglobulin‐like receptors (KIRs) …

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes

KJ Guinan, RT Cunningham, A Meenagh… - Genes & …, 2010 - nature.com
Natural killer (NK) cells are lymphocytes of the innate immune system. In humans, NK cell
activities are partly controlled by the diverse killer immunoglobulin-like receptor (KIR) gene …

Speed and selection in the evolution of killer‐cell immunoglobulin‐like receptors

J Martinez‐Borra, SI Khakoo - International journal of …, 2008 - Wiley Online Library
The killer‐cell immunoglobulin‐like receptors (KIR) form a diverse family of receptors that
control the functions of natural killer cells. Sequencing of KIR from primates has revealed the …

Deciphering the killer‐cell immunoglobulin‐like receptor system at super‐resolution for natural killer and T‐cell biology

V Béziat, HG Hilton, PJ Norman, JA Traherne - Immunology, 2017 - Wiley Online Library
Killer‐cell immunoglobulin‐like receptors (KIR s) are components of two fundamental
biological systems essential for human health and survival. First, they contribute to host …

[HTML][HTML] Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population

A Nakimuli, O Chazara, L Farrell, SE Hiby… - Immunogenetics, 2013 - Springer
Killer cell immunoglobulin-like receptor (KIR) genes are expressed by natural killer cells and
encoded by a family of genes exhibiting considerable haplotypic and allelic variation. HLA-C …

KIR and HLA under pressure: evidences of coevolution across worldwide populations

DG Augusto, ML Petzl-Erler - Human genetics, 2015 - Springer
KIR (killer cell immunoglobulin-like receptors) and HLA (human leukocyte antigens) are two
distinct gene families with remarkable importance for human immune responses. The …

Characterization of rhesus macaque KIR genotypes and haplotypes

PH Kruse, C Rosner, L Walter - Immunogenetics, 2010 - Springer
Certain combinations of the killer immunoglobulin-like receptors (KIR) and major
histocompatibility complex class I ligands in humans predispose carriers to a variety of …

MHC class I molecules and KIRs in human history, health and survival

P Parham - Nature reviews immunology, 2005 - nature.com
MHC class I molecules are ligands for the killer-cell immunoglobulin-like receptors (KIRs),
which are expressed by natural killer cells and T cells. The interactions between these …