Effective prevention of chronic postoperative pain is an important clinical goal, informed by a
growing body of studies. Peri‐operative regional anaesthesia remains one of the most …

Background Regional anaesthesia may reduce the risk of persistent (chronic) pain after
surgery, a frequent and debilitating condition. We compared regional anaesthesia vs …

Regional anaesthesia is able to reduce postoperative acute hyperalgesia and long-term
chronic pain by decreasing pain sensitization induced by the surgery itself, and …

Background Regional anaesthesia may reduce the rate of persistent (chronic) pain after
surgery, a frequent and debilitating condition. Objectives To compare local anaesthetics and …

Background Regional anesthesia may mitigate the risk of persistent postoperative pain
(PPP). This Cochrane review, published originally in 2012, was updated in 2017. Methods …

The development of chronic pain is considered a major complication after surgery. Basic
science research in animal models helps us understand the transition from acute to chronic …

This issue contains a report of the use of oral celecoxib to reduce acute perioperative pain
and prevent chronic postoperative pain. 1 It joins a list of interventions, many of them …

Background Regional anaesthesia may reduce the rate of persistent postoperative pain
(PPP), a frequent and debilitating condition. This review was originally published in 2012 …

Despite advances in our understanding of the neurobiology of nociception, postoperative
pain continues to be undertreated. There are many modalities that may provide effective …

Postoperative incisional pain is a unique and common form of acute pain. Because effective
postoperative analgesia reduces morbidity after surgery, new treatments continue to be …