[图书][B] In-Source, Droplet-Based Derivatization in an LC-MS Platform: Development, Validation, and Applications

DR Heiss - 2022 - search.proquest.com
Abstract As Analytical Chemists we are constantly demanding more of our methods: greater
selectivity, lower detection limits, wider utility, reduced complexity, etc. We are frequently …

Advances in coupling droplet microfluidics to mass spectrometry

BE Murray, LI Penabad, RT Kennedy - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•Droplet-MS offers selective, high-throughput analysis for low volume
samples.•Applications include drug screening, chemical reaction development, and in vivo …

“Development and application of analytical detection techniques for droplet-based microfluidics”-A review

W Liu, Y Zhu - Analytica Chimica Acta, 2020 - Elsevier
Droplet-based microfluidics has emerged as a powerful platform for high-throughput and low-
volume analysis and screening. At present, droplet-based microfluidics is transitioning from …

Droplet and digital microfluidics–enabled analytical techniques

K Gupta, Z Chen, K Gopinathan, A Mishra… - Droplet and Digital …, 2024 - Elsevier
Microfluidics has enabled the analysis of several biochemical phenomena crucial to life as
we know it. Encapsulation of target molecules, cells, or synthetic particles in micro and …

Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online

LM Fidalgo, G Whyte, BT Ruotolo… - Angewandte …, 2009 - Wiley Online Library
Emulsions created inside microfluidic devices have generated significant interest in recent
years because of their ability to compartmentalize reactions and assays on a microfluidic …

Interfacing droplet microfluidics with matrix-assisted laser desorption/ionization mass spectrometry: label-free content analysis of single droplets

SK Küster, SR Fagerer, PE Verboket, K Eyer… - Analytical …, 2013 - ACS Publications
Droplet-based microfluidic systems have become a very powerful tool to miniaturize
chemical and biological reactions. However, droplet content analysis remains challenging …

[PDF][PDF] Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis up to and Above 30Hz

E Kempa, C Smith, X Li, B Bellina, K Richardson… - ChemRxiv - academia.edu
High and ultra-high-throughput label-free sample analysis is required by many applications,
extending from environmental monitoring to drug discovery and industrial biotechnology …

Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature

NH Oberlies, SL Knowles, CSM Amrine, D Kao… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2019 The chemistry of nature can be beautiful, inspiring, beneficial and
poisonous, depending on perspective. Since the isolation of the first secondary metabolites …

Discovery in droplets

AK Price, BM Paegel - Analytical chemistry, 2016 - ACS Publications
In the summer of 2009, Daniel Chiu's prescient review in Analytical Chemistry described
droplet microfluidics, an emerging concept and malleable analytical tool. 1 The review …

Emerging microdroplet chemistry for synthesis and analysis

X Yan - International Journal of Mass Spectrometry, 2021 - Elsevier
Recent studies have shown that remarkable reaction acceleration can be achieved at the
air/solution interface of microdroplets. The unique environment of microdroplets can drive …