Background Peptic ulcer disease is common with a lifetime prevalence in the general
population of 5–10% and an incidence of 0.1–0.3% per year. Despite a sharp reduction in …

Introduction Every year peptic ulcer disease (PUD) affects 4 milion people around the world
[1]. Complications are encountered in 10%-20% of these patients and 2%-14% of the ulcers …

Background Perforated peptic ulcer (PPU) is a common surgical emergency that carries high
mortality and morbidity rates. Globally, one-quarter of a million people die from peptic ulcer …

Abstract Background/Aims: The incidence of uncomplicated peptic ulcer has decreased in
recent years. It is unclear what the impact of this has been on the epidemiology of peptic …

Peptic ulcer disease (PUD) affects 4 million people worldwide annually. The incidence of
PUD has been estimated at around 1.5% to 3%. Perforated peptic ulcer (PPU) is a serious …

Background Emergency surgery for perforated peptic ulcer (PPU) is associated with
significant morbidity and mortality. Accurate and early risk stratification is important. The …

Perforated peptic ulcer is a common emergency condition worldwide, with associated
mortality rates of up to 30%. A scarcity of high-quality studies about the condition limits the …

The incidence of peptic ulcer disease (PUD) peaked in the late 19th century while transiting
into the 20th century. With entry in the new millennium a significant decrease of PUD has …

The mortality associated with acute bleeding from a peptic ulcer remains high (5 to 10%),
and the condition accounts for more than 400,000 hospital admissions per year in the United …

Despite the introduction of histamine H2-receptor antagonists, proton-pump inhibitors and
the discovery of Helicobacter pylori, both the incidence of emergency surgery for perforated …