How can we better identify early HIV infections?

NE Rosenberg, CD Pilcher, MP Busch… - Current Opinion in HIV …, 2015 - journals.lww.com
There are important recent advances in detection of EHIs at the individual and population
levels. Applying optimal combinations of tests in diagnostic and HIV incidence algorithms is …

The detection and management of early HIV infection: a clinical and public health emergency

MK Smith, SE Rutstein, KA Powers… - JAIDS Journal of …, 2013 - journals.lww.com
This review considers the detection and management of early HIV infection (EHI), defined
here as the first 6 months of infection. This phase is clinically important because a reservoir …

The detection of acute HIV infection

MS Cohen, CL Gay, MP Busch… - The Journal of infectious …, 2010 - academic.oup.com
Acute human immunodeficiency virus (HIV) infection (AHI) can be defined as the time from
HIV acquisition until seroconversion. Incident HIV infection is less well defined but …

New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes

RS Janssen, GA Satten, SL Stramer, BD Rawal… - Jama, 1998 - jamanetwork.com
Context.—Differentiating individuals with early human immunodeficiency virus 1 (HIV-1)
infection from those infected for longer periods is difficult but important for estimating HIV …

[HTML][HTML] HIV diagnostic testing: evolving technology and testing strategies

D Daskalakis - Topics in antiviral medicine, 2011 - ncbi.nlm.nih.gov
Detection of acute HIV infection is important to public health because this stage is one of
high infectiousness and appears to account for a disproportionate amount of HIV …

[HTML][HTML] Acute HIV revisited: new opportunities for treatment and prevention

CD Pilcher, JJ Eron, S Galvin, C Gay… - The Journal of clinical …, 2004 - Am Soc Clin Investig
Inability to recognize incident infection has traditionally limited both scientific and public
health approaches to HIV disease. Recently, some laboratories have begun adding HIV …

Estimating the HIV incidence rate: recent and future developments

TB Hallett - Current Opinion in HIV and AIDS, 2011 - journals.lww.com
Estimating the HIV incidence rate: recent and future develop... : Current Opinion in HIV and
AIDS Estimating the HIV incidence rate: recent and future developments : Current Opinion in …

Testing for acute HIV infection: implications for treatment as prevention

SM Owen - Current Opinion in HIV and AIDS, 2012 - journals.lww.com
Continued improvements in technology and testing practice are vital for the success of HIV
prevention. Detection of acute or early HIV infection will likely play a key role in the success …

Surveillance for incident HIV infection: new technology and new opportunities

GW Rutherford, SK Schwarcz… - JAIDS Journal of …, 2000 - journals.lww.com
Although surveillance for HIV infection has traditionally focused on the incidence of AIDS
and the prevalence of HIV, new diagnostic technologies that allow the estimation of incident …

Beyond detuning: 10 years of progress and new challenges in the development and application of assays for HIV incidence estimation

MP Busch, CD Pilcher, TD Mastro, J Kaldor… - Aids, 2010 - journals.lww.com
In the ongoing battle against HIV/AIDS, it is critical that we are able to measure and monitor
HIV incidence, that is the number of new infections during a period of time, usually …