Variable accuracy, precision, and consistency of compounded famciclovir formulated for management of feline herpesvirus‐1 in cats

LM O'Leary, RA Allbaugh, DE Schrunk… - Veterinary …, 2021 - Wiley Online Library
Objective To evaluate compounded famciclovir suspensions for accuracy, precision, and
consistency in drug content. Procedures Two compounded famciclovir concentrations were …

Pharmacokinetics of famciclovir and penciclovir in tears following oral administration of famciclovir to cats: a pilot study

SM Thomasy, JC Covert, SD Stanley… - Veterinary …, 2012 - Wiley Online Library
Objective To validate a means of collecting tears from cats, develop an assay for quantifying
famciclovir and penciclovir in tears, and to assess famciclovir and penciclovir concentrations …

Evaluation of compounded cidofovir, famciclovir, and ganciclovir for the treatment of feline herpesvirus ocular surface disease in shelter‐housed cats

MA Mironovich, A Yoon, ME Marino… - Veterinary …, 2023 - Wiley Online Library
Objective To assess the efficacy of compounded cidofovir, famciclovir, and ganciclovir for the
treatment of feline herpesvirus type 1 (FHV‐1) ocular surface disease. Animals studied 132 …

In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites

AD Groth, MT Contreras, HK Kado‐Fong… - Veterinary …, 2014 - Wiley Online Library
Objectives To assess in vitro the antiviral efficacy against feline herpesvirus (FHV‐1) and
cytotoxicity for cultured feline cells of famciclovir and its metabolites, BRL 42359 and …

Oral administration of famciclovir for treatment of spontaneous ocular, respiratory, or dermatologic disease attributed to feline herpesvirus type 1: 59 cases (2006 …

SM Thomasy, O Shull, CA Outerbridge… - Journal of the …, 2016 - Am Vet Med Assoc
OBJECTIVE To evaluate outcomes for cats treated with orally administered famciclovir 3
times/d for clinical signs attributed to naturally occurring feline herpesvirus type 1 (FHV-1) …

Evaluation of orally administered famciclovir in cats experimentally infected with feline herpesvirus type-1

SM Thomasy, CC Lim, CM Reilly… - American Journal of …, 2011 - Am Vet Med Assoc
Objective—To evaluate orally administered famciclovir for treatment of cats with
experimentally induced disease attributable to feline herpesvirus type-1 (FHV-1). Animals …

In vitro efficacy of ganciclovir against feline herpesvirus type 1 and assessment of ocular tolerability in healthy cats

AC Lewin, CC Liu, C Alling… - Journal of Feline …, 2021 - journals.sagepub.com
Objectives Feline herpesvirus-1 (FHV-1) is a prevalent cause of ocular disease in cats and
limited topical options for treatment currently exist. The first objective of this study was to …

Pharmacokinetic modeling of penciclovir and BRL42359 in the plasma and tears of healthy cats to optimize dosage recommendations for oral administration of …

L Sebbag, SM Thomasy, AP Woodward… - American Journal of …, 2016 - Am Vet Med Assoc
OBJECTIVES To determine, following oral administration of famciclovir, pharmacokinetic
(PK) parameters for 2 of its metabolites (penciclovir and BRL42359) in plasma and tears of …

Pharmacokinetics and safety of penciclovir following oral administration of famciclovir to cats

SM Thomasy, DJ Maggs, NK Moulin… - American journal of …, 2007 - Am Vet Med Assoc
Objective—To investigate penciclovir pharmacokinetics following single and multiple oral
administrations of famciclovir to cats. Animals—8 adult cats. Procedures—A balanced …

Comparative efficacy of topical ophthalmic ganciclovir and oral famciclovir in cats with experimental ocular feline herpesvirus-1 epithelial infection

EC Ledbetter, ZI Badanes, RX Chan… - Journal of Ocular …, 2022 - liebertpub.com
Purpose: To determine the comparative efficacy of ganciclovir ophthalmic gel and
famciclovir oral tablets in cats with experimentally induced ocular feline herpesvirus-1 (FHV …