[HTML][HTML] Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon

E Ofon, H Noyes, V Ebo'o Eyanga… - PLoS Neglected …, 2019 - journals.plos.org
Background Human African Trypanosomiasis (HAT) is a neglected tropical disease caused
by infections due to Trypanosoma brucei subspecies. In addition to the well-established …

[HTML][HTML] A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

E Ofon, H Noyes, J Mulindwa, H Ilboudo… - PLoS Neglected …, 2017 - journals.plos.org
Background Human African Trypanosomiasis (HAT) is a neglected disease targeted for
elimination as a public health problem by 2020. Elimination requires a better understanding …

[HTML][HTML] Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea

JW Kabore, H Ilboudo, H Noyes… - PLoS Neglected …, 2017 - journals.plos.org
Background Human African trypanosomiasis (HAT), a lethal disease induced by
Trypanosoma brucei gambiense, has a range of clinical outcomes in its human host in West …

Association between human African trypanosomiasis and the IL6 gene in a Congolese population

D Courtin, J Milet, V Jamonneau, CS Yeminanga… - Infection, Genetics and …, 2007 - Elsevier
Despite the importance of behavioural and environmental risk factors, there are arguments
consistent with the existence of a genetic susceptibility to human African trypanosomiasis …

[HTML][HTML] Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire

B Ahouty, M Koffi, H Ilboudo, G Simo… - PLoS Neglected …, 2017 - journals.plos.org
Human African Trypanosomiasis (HAT) or sleeping sickness is a Neglected Tropical
Disease. Long regarded as an invariably fatal disease, there is increasing evidence that …

Interest of tumor necrosis factor-alpha− 308 G/A and interleukin-10− 592 C/A polymorphisms in human African trypanosomiasis

D Courtin, L Argiro, V Jamonneau, L N'dri… - Infection, Genetics and …, 2006 - Elsevier
This study aimed to determine whether single nucleotide polymorphisms (SNPs) within
tumour necrosis factor-alpha (TNF) and interleukin-10 (IL10) promoters and genes are …

[HTML][HTML] Relationship between Trypanosoma brucei rhodesiense genetic diversity and clinical spectrum among sleeping sickness patients in Uganda

CD Kato, CM Mugasa, A Nanteza, E Matovu… - BMC Research …, 2017 - Springer
Abstract Objective Human African trypanosomiasis (HAT) due to Trypanosoma brucei
rhodesiense in East and southern Africa is reported to be clinically diverse. We tested the …

[HTML][HTML] HLA-G 3'UTR 14 bp Insertion Is Associated with a Decreased Risk of Developing Human African Trypanosomiasis in the Côte d'Ivoire Population

B Ahouty, M Koffi, D Courtin, I Hamidou… - Open Journal of …, 2019 - scirp.org
Human African trypanosomiasis (HAT), or sleeping sickness, caused by Trypanosoma
brucei gambiense, is associated with diverse clinical outcomes. Host's genetic factors …

A Genome-Wide Association Study Reveals Novel Genetic Markers Associated with Human African Trypanosomiasis

J Mulindwa, MP Kimuda, H Noyes, H Ilboudo, M Koffi… - medRxiv, 2024 - medrxiv.org
Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense cause human
African trypanosomiasis (HAT), a neglected tropical disease that constitutes an important …

[HTML][HTML] No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

MP Kimuda, H Noyes, J Mulindwa… - PLoS neglected …, 2018 - journals.plos.org
Background Human African trypanosomiasis (HAT) manifests as an acute form caused by
Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei …