Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among
which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor …

As one type of the most important alkaloids in the world, terpenoid indole alkaloids (TIAs)
show a wide range of pharmaceutical activities that are beneficial for clinical treatments …

In order to improve the production of the anticancer dimeric indole alkaloids in
Catharanthuse roseus, much research has been dedicated to culturing cell lines, hairy roots …

Biosynthesis of medicinally valuable terpenoid indole alkaloids (TIAs) in Catharanthus
roseus is regulated by transcriptional activators such as the basic helix–loop–helix factor …

Terpenoid indole alkaloid (TIA) biosynthesis in Catharanthus roseus is a complex and highly
regulated process. Understanding the biochemistry and regulation of the TIA pathway is of …

NAC transcription factors (TFs) are crucial to growth and defense responses in plants.
Though NACs have been characterized for their role in several plants, comprehensive …

Catharanthus roseus produces bioactive terpenoid indole alkaloids (TIA s), including the
chemotherapeutics, vincristine and vinblastine. Transcriptional regulation of TIA …

Key message The novel AP2/ERF transcription factor SmERF128 positively regulates
diterpenoid tanshinone biosynthesis by activating the expression of SmCPS1, SmKSL1, and …

The monoterpene indole alkaloids (MIAs) are generally derived from strictosidine, which is
formed by condensation of the terpene moiety secologanin and the indole moiety …

Abstract Background The medicinal plant, Catharanthus roseus (C. roseus), accumulates a
wide range of terpenoid indole alkaloids (TIAs). Ethylene (ET) and methyl-jasmonate (MeJA) …