Intranasal (IN) drug delivery is a non-invasive and effective route for the administration of
drugs to the brain at pharmacologically relevant concentrations, bypassing the blood–brain …

The brain is the most delicate, complex, and vital organ of the human body, and is highly
protected by different protective structures including skull, meninges, cerebrospinal fluid …

Background: The convoluted pathophysiology of brain disorders along with penetration
issue of drugs to brain represents major hurdle that requires some novel therapies. The …

The blood-brain barrier (BBB) has a very significant role in drug delivery to the brain, which
allows passes of only a few molecules. Conventional drug delivery systems have very …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Advancements in neurosciences lead to the development of potential therapeutics that are
capable of altering pathophysiology and mitigate neurological disorders but are inefficient …

Nanotechnology has proved its tremendous worth in the field of drug delivery and targeting.
Nano formulations have improved the safety and efficacy of various conventional drugs …

Blood-brain barrier (BBB) provides restrictions for the transportation of various therapeutic
agents to the brain. Efforts to directly target the brain by olfactory as well as trigeminal nerve …

Background: Current cerebral drug delivery to the brain and Cerebrospinal Fluid (CSF) is
limited by the Blood-Brain Barrier (BBB) or the blood-blood Cerebrospinal Fluid (CSF) …

The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …