The integration of radiotherapy with immunotherapy for the treatment of non–small cell lung cancer
EC Ko, D Raben, SC Formenti - Clinical Cancer Research, 2018 - AACR
Five-year survival rates for non–small cell lung cancer (NSCLC) range from 14% to 49% for
stage I to stage IIIA disease, and are< 5% for stage IIIB/IV disease. Improvements have been …
stage I to stage IIIA disease, and are< 5% for stage IIIB/IV disease. Improvements have been …
[HTML][HTML] Clinical trials integrating immunotherapy and radiation for non–small-cell lung cancer
ME Daly, AM Monjazeb, K Kelly - Journal of Thoracic Oncology, 2015 - Elsevier
Methods of harnessing the immune system to treat cancer have been investigated for
decades, but yielded little clinical progress. However, in recent years, novel drugs that allow …
decades, but yielded little clinical progress. However, in recent years, novel drugs that allow …
Combined treatment of non‐small cell lung cancer using radiotherapy and immunotherapy: challenges and updates
S Shang, J Liu, V Verma, M Wu, J Welsh… - Cancer …, 2021 - Wiley Online Library
The efficacy of immunotherapy for advanced non‐small cell lung cancer (NSCLC) remains
unsatisfactory, as the majority of patients either do not experience an objective response or …
unsatisfactory, as the majority of patients either do not experience an objective response or …
[HTML][HTML] Immunotherapy in lung cancer
E Massarelli, V Papadimitrakopoulou… - … lung cancer research, 2014 - ncbi.nlm.nih.gov
Survival rates for metastatic lung cancer including non-small cell lung cancer (NSCLC) and
small cell lung cancer (SCLC) are poor with 5-year survival of less than 5%. The use of …
small cell lung cancer (SCLC) are poor with 5-year survival of less than 5%. The use of …
Chemoradioimmunotherapy of inoperable stage III non-small cell lung cancer: immunological rationale and current clinical trials establishing a novel multimodal …
L Käsmann, C Eze, J Taugner, O Roengvoraphoj… - Radiation …, 2020 - Springer
Immune-checkpoint inhibitors (ICI) have dramatically changed the landscape of lung cancer
treatment. Preclinical studies investigating combination of ICI with radiation show a …
treatment. Preclinical studies investigating combination of ICI with radiation show a …
Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state …
L Wu, Z Zhang, M Bai, Y Yan, J Yu, Y Xu - Cell Communication and …, 2023 - Springer
Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …
concurrently with chemotherapy was recommended for unresectable, locally advanced non …
[HTML][HTML] Combining immunotherapy and radiotherapy in lung cancer
N Bhalla, R Brooker, M Brada - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
Immunotherapy has become standard of care in advanced non-small cell lung cancer
(NSCLC) in a number of settings. Radiotherapy remains an important and potentially …
(NSCLC) in a number of settings. Radiotherapy remains an important and potentially …
Impact of radiation dose to the host immune system on tumor control and survival for stage III non-small cell lung cancer treated with definitive radiation therapy
Purpose The significance of radiation dose to the host immune system during the treatment
of stage III non-small cell lung cancer (NSCLC) is unknown, but higher doses were …
of stage III non-small cell lung cancer (NSCLC) is unknown, but higher doses were …
[HTML][HTML] Novel radiotherapy approaches for lung cancer: combining radiation therapy with targeted and immunotherapies
Targeted therapies and immunotherapies have quickly become fixtures in the treatment
armamentarium for metastatic non-small cell lung cancer (NSCLC). Targeted therapies …
armamentarium for metastatic non-small cell lung cancer (NSCLC). Targeted therapies …
[HTML][HTML] Radiation and immunotherapy: emerging mechanisms of synergy
Immunotherapy (IO) has become a standard treatment in patients with metastatic and locally
advanced non-small cell lung cancer (NSCLC), and is now being tested in patients with …
advanced non-small cell lung cancer (NSCLC), and is now being tested in patients with …