Bacterial cell walls are composed of the large cross‐linked macromolecule peptidoglycan,
which maintains cell shape and is responsible for resisting osmotic stresses. This is a highly …

Peptidoglycan is the predominant stress‐bearing structure in the cell envelope of most
bacteria, and also a potent stimulator of the eukaryotic immune system. Obligate intracellular …

Role of transmembrane heparan sulfate proteoglycans on invasion of Orientia
tsutsugamushi into host cells was investigated. Pretreatment with heparan sulfate and …

Our understanding of the molecular systems that bacteria have developed over millennia of
evolutionary tinkering remains limited compared with the incredible diversity of the bacterial …

Orientia tsutsugamushi, the causative agent of scrub typhus, is an obligate intracellular
pathogen. Previously, we reported that the 56-kDa type-specific antigen (TSA56), a major …

Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host
interaction. The genome sequencing, microarray and proteomic analyses of this ancient …

Orientia tsutsugamushi (Ot) is an obligate intracellular bacterium in the family Rickettsiaceae
that causes scrub typhus, a severe mite-borne human disease. Its mechanism of cell exit is …

The fundamental polymer that is a common component of the cell walls of Grampositive and
Gram-negative bacteria, Rickettsiae and blue-green bacteria is called peptidoglycan …

Orientia tsutsugamushi is an etiologic agent of scrub typhus, a globally emerging
rickettsiosis that can be fatal. The bacterium's obligate intracellular lifestyle requires its …

The cytoplasm of bacteria is maintained at a higher osmolality than the growth medium,
which generates a turgor pressure. The cell membrane (CM) cannot support a large turgor …