Molecular probe that enables in vivo imaging is the cornerstone of accurate disease
diagnosis, prognostic estimation, and therapies. Although several nucleic acid-based …

Programming ultrasensitive and stimuli-responsive DNAzyme-based probes that contain
logic gate biocomputation hold great potential for precise molecular imaging. In this work, a …

Conspectus The pursuit of in-depth studying the nature and law of life activity has been
dominating current research fields, ranging from fundamental biological studies to …

Dynamic nucleic acid-based biocircuits have spurred substantial research efforts for
diagnosis or biomedical applications at the molecular level; nevertheless, it still remains a …

Catalytic DNA circuit, a versatile synthetic molecular nanodevice, shows great potential for in
vivo bioimaging application, yet is distorted by its off-site signal leakage. The endogenously …

Catalytic DNA circuits are desirable for sensitive bioimaging in living cells; yet, it remains a
challenge to monitor these intricate signal communications because of the uncontrolled …

Catalytic DNA circuits represent a versatile toolbox for tracking intracellular biomarkers yet
are constrained with low anti-interference capacity originating from their severe off-site …

Conspectus With unparalleled programmability, DNA has evolved as a powerful scaffold for
engineering intricate and dynamic systems that can perform diverse tasks. By allowing serial …

Synthetic DNA motors have spurred considerable research interest as a way to interrogate
biochemical processes that can further facilitate disease diagnosis. However, current direct …

Artificial catalytic DNA circuits that can identify, transduce and amplify the biomolecule of
interest have supplemented a powerful toolkit for visualizing various biomolecules in cancer …