Kay Jann1, Xingfeng Shao1, Samantha J. Ma1, Steven Y. Cen2, Lina D'Orazio2, Giuseppe Barisano3, Lirong Yan1, Marlena Casey1, Jesse Lamas1, Adam M …

SH Joshi, J Guo - … imaging—from micro-to macroscopic scales, 2022 - books.google.com
MoCA scores, controlling for age, gender, years of education, and testing language. Relative
CBF in WM was negatively correlated with WMH volume and MoCA scores, while relative …

[HTML][HTML] Evaluation of cerebral blood flow measured by 3D PCASL as biomarker of vascular cognitive impairment and dementia (VCID) in a cohort of elderly latinx …

K Jann, X Shao, SJ Ma, SY Cen, L D'Orazio… - Frontiers in …, 2021 - frontiersin.org
Cerebral small vessel disease (cSVD) affects arterioles, capillaries, and venules and can
lead to cognitive impairments and clinical symptomatology of vascular cognitive impairment …

[HTML][HTML] Perfusion heterogeneity of cerebral small vessel disease revealed via arterial spin labeling MRI and machine learning

W Lu, C Yu, L Wang, F Wang, J Qiu - NeuroImage: Clinical, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is associated with altered cerebral perfusion.
However, global and regional cerebral blood flow (CBF) are highly heterogeneous across …

[HTML][HTML] Decreased cerebral blood flow and delayed arterial transit are independently associated with white matter hyperintensity

R Zhang, P Huang, S Wang, Y Jiaerken… - Frontiers in Aging …, 2022 - frontiersin.org
Aim White matter hyperintensities (WMH) and lacunes were important features of cerebral
small vessel disease (CSVD), which contributes to 25% of ischemic strokes and 45% of …

[HTML][HTML] Microvascular impairment in patients with cerebral small vessel disease assessed with arterial spin labeling magnetic resonance imaging: a pilot study

K Neumann, M Günther, E Düzel… - Frontiers in aging …, 2022 - frontiersin.org
In this pilot study, we investigated microvascular impairment in patients with cerebral small
vessel disease (CSVD) using non-invasive arterial spin labeling (ASL) magnetic resonance …

Advanced neuroimaging to unravel mechanisms of cerebral small vessel diseases

ME Gurol, GJ Biessels, JR Polimeni - Stroke, 2020 - Am Heart Assoc
30 Stroke January 2020 resonance imaging (MRI) also added new lesion types to the list of
the classically accepted cSVD-related pathologies. ICH and CMBs in deep-brain regions …

Vascular biology of dementia

MJ Cipolla, NJ Alkayed - Stroke, 2023 - Am Heart Assoc
Central neurons have an essential need for a constant energy substrate that must be
coordinated and driven by the cerebral circulation. Cerebral blood flow is highly …

[PDF][PDF] Published Ahead of Print on March 24, 2021 as 10.1212/WNL. 0000000000011783

D Kerkhofs, SM Wong, E Zhang, J Staals, FA Jansen… - 2021 - researchgate.net
Objective To investigate the two-year change in parenchymal diffusivity, a quantitative
marker of microstructural tissue condition, and the relationship with baseline blood-brain …

Pooled cohort risk equation and subclinical cerebrovascular diseases

KW Nam, HM Kwon, HY Jeong, JH Park… - European Journal of …, 2020 - Wiley Online Library
Background and purpose In 2013, the American College of Cardiology/American Heart
Association (ACC/AHA) introduced a novel pooled cohort risk (PCR) model for …

[HTML][HTML] Caliber of intracranial arteries as a marker for cerebral small vessel disease

Z Chen, H Li, M Wu, C Chang, X Fan, X Liu… - Frontiers in …, 2020 - frontiersin.org
Background: The dilation of intracranial large arteries caliber, may transfer more
hemodynamic burden to the downstream brain capillaries, which, in the long run, results in …