[HTML][HTML] Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights

MA Hannan, MS Zahan, PP Sarker, A Moni… - International Journal of …, 2021 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and a close
association between acute kidney injury (AKI) and CKD has recently been identified. Black …

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review

E Sadeghi, M Imenshahidi, H Hosseinzadeh - Molecular Biology Reports, 2023 - Springer
Background Nigella sativa and its main bioactive ingredient, thymoquinone, exhibit various
pharmacological activities, including neuroprotective, nephroprotective, cardioprotective …

[HTML][HTML] The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review

A Ragheb, A Attia, WS Eldin, F Elbarbry… - Saudi Journal of …, 2009 - journals.lww.com
Abstract Thymoquinone (TQ), 2-Isopropyl-5-methyl-1, 4-benzoquinone, is one of the most
active ingredients of Nigella Sativa seeds. TQ has a variety of beneficial properties including …

An overview on renoprotective effects of thymoquinone

H Shaterzadeh-Yazdi, MF Noorbakhsh… - Kidney …, 2018 - karger.com
Background: Kidneys as vital organs remove waste material from blood. Additionally, they
may also have a role in the electrolyte balance, regulation of blood pressure, and red blood …

Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities

Y Cai, C Huang, M Zhou, S Xu, Y Xie, S Gao, Y Yang… - Phytomedicine, 2022 - Elsevier
Background Acute kidney injury (AKI) is a common complication in clinical inpatients, and it
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …

[HTML][HTML] Nephroprotective activity of naringin against chemical-induced toxicity and renal ischemia/reperfusion injury: A review

N Amini, M Maleki, M Badavi - Avicenna Journal of Phytomedicine, 2022 - ncbi.nlm.nih.gov
Objective: The kidney is well-known as the vital organ which is responsible for maintaining
body homeostasis and secretion of toxic metabolites. Renal injury is accompanied by …

Effect of thymoquinone on acute kidney injury induced by sepsis in BALB/c mice

LP Guo, SX Liu, Q Yang, HY Liu, LL Xu… - Biomed research …, 2020 - Wiley Online Library
Acute kidney injury (AKI) is a common complication of sepsis and has also been observed in
some patients suffering from the new coronavirus pneumonia COVID‐19, which is currently …

[HTML][HTML] Renal injury, nephrolithiasis and Nigella sativa: A mini review

P Hayatdavoudi, AK Rad, Z Rajaei… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Objective: The incidence and prevalence of kidney stone is increasing worldwide. After the
first recurrence the risk of subsequent relapses is higher and the time period between …

Thymoquinone ameliorates cadmium-induced nephrotoxicity, apoptosis, and oxidative stress in rats is based on its anti-apoptotic and anti-oxidant properties

M Erboga, M Kanter, C Aktas, U Sener… - Biological trace element …, 2016 - Springer
Cadmium (Cd), an environmental and industrial pollutant, generates free radicals
responsible for oxidative stress. Cd can also lead to various renal toxic damage such as the …

Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling

M Al Fayi, H Otifi, M Alshyarba, AA Dera… - Journal of Drug …, 2020 - Taylor & Francis
This study evaluates the protective effects of Thymoquinone (Tq) and Curcumin (Cur) in
models of cisplatin-induced renal toxicity. Proliferation studies were carried out in HEK-293 …