The kinetics of deoxyhemoglobin S gelation have been investigated using photolytic
dissociation of the carbon monoxide complex to initiate the process. Measurements over a …

We report the results of a kinetic investigation on the gelation of purified deoxyhemoglobin
S. Gelation was induced by raising the temperature and was monitored by measuring both …

Using a combination of laser photolysis and temperature-jump techniques, the kinetics of
hemoglobin S polymerization have been studied over a wide range of delay times (10− 3 to …

We describe a technique for monitoring the kinetics of sickle cell hemoglobin gelation by
observing the change in the amplitude and linewidth of the water proton magnetic …

This paper describes the thermodynamic behavior of gels of deoxyhemoglobin S. The
solubility of the protein with respect to assembled hemoglobin fibers has been measured …

The homogeneous nucleation rate for sickle hemoglobin polymerization has been
measured for concentrations from 3.9 to 4.9 mM and temperatures from 13 degrees C to 35 …

We report the results of thermodynamic and kinetic studies on the gelation of mixtures of
sickle cell (S) deoxyhemoglobin with normal human adult (A) and fetal (F) …

A new, crystalline state of deoxygenated sickle hemoglobin is described which is formed
spontaneously in agitated concentrated hemoglobin S solutions under conditions otherwise …

A laser photolysis technique has been developed to assess the quantitative significance of
the delay time of hemoglobin S gelation to the pathophysiology of sickle cell disease …

We have used two techniques to characterize the gelation of deoxyhemoglobin S, a high
sensitivity heat-flow calorimeter to measure the heat of gelation and a simple light …