Clin Microbiol Infect 2012; 18 (Suppl. 5): 7–14 Abstract Streptococcus pneumoniae causes
different types of acute, invasive and non‐invasive clinical infections, being the most …

To overview the present global burden of pneumococcal disease is important because new
preventive measures such as the pneumococcal conjugate vaccine 13 are currently being …

Individuals< 2 years and≥ 50 years of age, as well as those with other specific risk factors,
are especially vulnerable to invasive pneumococcal disease (IPD). Conjugate vaccines …

Pneumococcal disease constitutes a major global health problem. Adults aged over 50
years and younger adults with specific chronic health conditions are at risk for invasive …

Background. Although it is widely accepted that adults with immunocompromising conditions
are at greatly increased risk of pneumococcal infection, the extent of risk among …

Background The burden of invasive pneumococcal disease in young children decreased
dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) …

Streptococcus pneumoniae related diseases are a leading cause of morbidity and mortality,
especially in children and in the elderly population. It is transmitted to other individuals …

Rationale: New vaccines are urgently needed to protect the vulnerable from bacterial
pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens of …

Pneumococcal infections continue to cause significant morbidity and mortality in patients
throughout the world. This microorganism remains the most common bacterial cause of …

Infection with Streptococcus pneumoniae remains a major global health burden meaning
the development of effective vaccines is urgently needed. The current 23-valent …