Background: The acute phase of abstinence from methamphetamine abuse is critical for
rehabilitation success. Proton magnetic resonance spectroscopy has detected below-normal …

Introduction Chronic methamphetamine use results in persistent neuropsychological deficits
in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis …

Methamphetamine (METH) is a stimulant drug that is toxic primarily to dopaminergic and
serotonergic neurons and may lead to inflammatory changes in the brain. Additionally, the …

Background Methamphetamine induces neuronal N-acetyl-aspartate synthesis in preclinical
studies. In a preliminary human proton magnetic resonance spectroscopic imaging …

Mu-opioid receptor agonists alter brain glutamate (GLU) levels in laboratory animals. This
clinical study used proton magnetic resonance spectroscopy (1 H MRS) to examine regional …

Background Abnormal patterns of metabolite levels have been detected by magnetic
resonance spectroscopy in frontostriatal regions of individuals meetingDSM-IVcriteria for …

Background Abuse of methamphetamine (MA) is a global health concern. Previous 1 H-
MRS studies have found that, with methamphetamine abstinence (MAA), there are changes …

Abstract Background 3, 4-Methylenedioxymethamphetamine (MDMA) is a widely used
recreational substance inducing acute release of serotonin. Previous studies in chronic …

Persistent neurochemical abnormalities in frontal brain structures are believed to result from
methamphetamine use. We developed a localized 13C magnetic resonance spectroscopy …

Studies based on animal models report that methamphetamine (MA) abuse diminishes
dopamine (DA) and serotonin innervation in frontal brain regions. In this in vivo human …