More than a decade of research has shown that Sertoli cell proliferation is regulated by
thyroid hormone. Neonatal hypothyroidism lengthens the period of Sertoli cell proliferation …

Whereas spermatogonia stem cells continually divide to populate the testis with developing
germ cells, the major supporter of this process, the Sertoli cell, ceases to proliferate shortly …

Thyroid hormone inhibits neonatal Sertoli cell proliferation and recent results have shown
that thyroid hormone upregulates cyclin-dependent kinase inhibitors (CDKIs) p27Kip1 and …

Thyroid hormone regulates early postnatal Sertoli cell proliferation. Transient neonatal
hypothyroidism allows prolonged postnatal Sertoli cell mitogenesis and doubles adult …

Hypo-and hyperthyroidism alter testicular functions in the young. Among T3 receptors,
TRalpha1 is ubiquitous, and its previously described knockout leads to an increase in testis …

Neonatal hypothyroidism increases adult Sertoli cell populations by extending Sertoli cell
proliferation. Conversely, hyperthyroidism induces premature cessation of Sertoli cell …

This study uses a high purity cell culture system to extend previous observations of factors
controlling the end of the Sertoli cell proliferative phase. Thyroid hormone, retinoic acid, and …

Sertoli cell proliferation in the rat is completed by Days 15–20 postnatally. Thyroid hormones
appear to regulate the duration of Sertoli cell proliferation, affecting adult Sertoli cell number …

Thyroid hormone is a critical regulator of growth, development and metabolism in virtually all
tissues, and altered thyroid status affects many organs and systems. Although for many …

Thyroid hormones are emerging regulators of testicular function since Sertoli, germ, and
Leydig cells are found to express thyroid hormone receptors (TRs). These testicular cells …