Isobiotic mice, with an identical stable microbiota composition, potentially allow models of
host-microbial mutualism to be studied over time and between different laboratories. To …

The mammalian gut harbors complex and variable microbial communities, across both host
phylogenetic space and conspecific individuals. A synergy of host genetic and …

In vertebrates, including humans, individuals harbor gut microbial communities whose
species composition and relative proportions of dominant microbial groups are …

Identifying a common set of genes that mediate host–microbial interactions across
populations and species of mammals has broad relevance for human health and animal …

Mammals exhibit marked interindividual variations in their gut microbiota, but it remains
unclear if this is primarily driven by host genetics or by extrinsic factors like dietary intake. To …

The proportion of the human gut bacterial community that is recalcitrant to culture remains
poorly defined. In this report, we combine high-throughput anaerobic culturing techniques …

Gut microbial community properties of mammals are thought to be partly shaped by a
combination of host immunity and environmental factors, but their relative importance is not …

Background Normal mammalian development and homeostasis are dependent upon the gut
microbiota. Antibiotics, essential for the treatment and prophylaxis of bacterial infections, can …

Despite the fundamental contribution of the gut microbiota to host physiology, the extent of
its variation in genetically-identical animals used in research is not known. We report …

The intestinal microbiota is a fundamental factor that broadly influences physiology. Thus,
studies using transgenic animals should be designed to limit the confounding effects of …