Occupational silica exposure caused a serious disease burden of silicosis. There is currently
a lack of sensitive and effective biomarkers for silicosis, and the pathogenesis of silicosis is …

Purpose The degree of silicosis exposure is closely related to the progress of silicosis. At
present, we use animal and human studies to explore whether silicon can be an important …

Background Silicosis shows an increasing trend with the development of new industries.
However, the potential biomarkers for predicting the disease severity are lacking. A novel …

The aim of the present study was to investigate the correlation between tumor necrosis factor-
alpha (TNF-α) and interleukin (IL)-12p40-containing cytokines, in silicosis patients and …

Objective: To study roles of Clara cell protein 16 (CC16) and surfactant protein-D (SP-D) as
serum biomarkers in the early diagnosis and the pathogenesis of silicosis. Methods: Thirty …

Rationale: effective therapies for silicosis, so early screening susceptible individuals and
early diagnosis and intervention are very important. All of these require a high sensitivity and …

Silicosis, induced by inhaling silica particles in workplaces, is one of the most common
occupational diseases. The prognosis of silicosis and its consequent fibrosis is extremely …

Silicosis is an important industrial health problem for those workers exposed to silica. The
present study aimed to investigate the sensitivity and specificity of combined detection of …

Objective We aimed to evaluate the enzyme activity of chitotriosidase as a biomarker in early
diagnosis silicosis and to investigate immune system response and oxidative stress caused …

Background The identification of markers that can facilitate the early diagnosis of silicosis
has remained challenging. We evaluated the association of inflammatory markers with the …