The dimethyhydrazine (DMH) or azoxymethane (AOM) model is a well‐established, well‐
appreciated, and widely used model of experimental colon carcinogenesis. It has many …

Animal models of colorectal carcinogenesis represent invaluable research tool for
investigating colorectal cancer (CRC). Experimentally induced tumours in laboratory …

dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating
agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon …

Azoxymethane (AOM) is an organotropic colon carcinogen that is commonly used to induce
colon tumors in rodents. Unlike its parent compound, 1, 2-dimethylhydrazine (DMH), a tumor …

The effects of multiple dietary influences on 1, 2-dimethylhydrazine [(DMH) CAS: 540-73-8]-
induced colon cancer in rats were studied. A 24 factorial experimental design was used to …

1, 2-Dimethylhydrazine (DMH) is a potent colon carcinogen that is commonly used as an
initiator in studies of the effects of diet on colon cancer. Previous studies have shown that …

The azoxymethane (AOM) model has been widely used to investigate the pathology and
genetics of colorectal cancer in rodents. However, there has been wide variation in …

Azoxymethane (AOM) is a colon carcinogen that is used to study the pathogenesis of
sporadic colorectal cancer. We have evaluated differential susceptibility to AOM in inbred …

We have recently developed a mouse model for colitis-related colon carcinogenesis by a
combined treatment with azoxymethane (AOM) and dextran sodium sulfate (DSS) in male …

To shed light on the association of intestinal microflora with the development of colon
cancer, we studied the modifying effects of intestinal microflora on the occurrence of 1, 2 …