Understanding the pathophysiological mechanisms of cardiometabolic complications in obstructive sleep apnoea: towards personalised treatment approaches

S Ryan, EP Cummins, R Farre… - European …, 2020 - Eur Respiratory Soc
In January 2019, a European Respiratory Society research seminar entitled “Targeting the
detrimental effects of sleep disturbances and disorders” was held in Dublin, Ireland. It …

[HTML][HTML] Obstructive sleep apnoea and cardiovascular consequences: pathophysiological mechanisms

C Arnaud, T Bochaton, JL Pépin, E Belaidi - Archives of cardiovascular …, 2020 - Elsevier
Obstructive sleep apnoea syndrome is a growing health concern, affecting nearly one billion
people worldwide; it is an independent cardiovascular risk factor, associated with incident …

OSA and cardiometabolic risk: W hat's the bottom line?

CM Hoyos, LF Drager, SR Patel - Respirology, 2017 - Wiley Online Library
Obstructive sleep apnoea (OSA) is a common condition characterized by repetitive upper
airway obstruction during sleep. OSA promotes wide intrathoracic pressure swings …

Mechanisms of apnea

DJ Eckert, A Malhotra, AS Jordan - Progress in cardiovascular diseases, 2009 - Elsevier
This paper focuses on the underlying mechanisms contributing to sleep-disordered
breathing. Obstructive sleep apnea (OSA) is the most common sleep-related breathing …

Sleep-disordered breathing, type 2 diabetes and the metabolic syndrome

IW Seetho, JPH Wilding - Chronic respiratory disease, 2014 - journals.sagepub.com
Sleep-disordered breathing (SDB) encompasses a spectrum of conditions that can lead to
altered sleep homeostasis. In particular, obstructive sleep apnoea (OSA) is the most …

[HTML][HTML] Sleep apnoea

JC Jun, S Chopra, AR Schwartz - European Respiratory …, 2016 - Eur Respiratory Soc
Sleep apnoea is a disorder characterised by repetitive pauses in breathing during sleep
caused by airway occlusion (obstructive sleep apnoea) or altered control of breathing …

New frontiers in obstructive sleep apnoea

NT Ayas, AAJ Hirsch, I Laher, TD Bradley… - Clinical …, 2014 - portlandpress.com
OSA (obstructive sleep apnoea), the most common respiratory disorder of sleep, is caused
by the loss of upper airway dilating muscle activity during sleep superimposed on a narrow …

Sleep apnoea syndrome in 2011: current concepts and future directions

P Lévy, R Tamisier, C Minville… - European Respiratory …, 2011 - Eur Respiratory Soc
In the past two decades, obstructive sleep apnoea (OSA) has been identified as a common
clinical condition. Epidemiological studies have confirmed a high prevalence of the disease …

Biological plausibility linking sleep apnoea and metabolic dysfunction

A Gileles-Hillel, L Kheirandish-Gozal… - Nature Reviews …, 2016 - nature.com
Obstructive sleep apnoea (OSA) is a very common disorder that affects 10–25% of the
general population. In the past two decades, OSA has emerged as a cardiometabolic risk …

Advances and challenges in pursuing biomarkers for obstructive sleep apnea: implications for the cardiovascular risk

A Lebkuchen, LS Freitas, KHM Cardozo… - Trends in cardiovascular …, 2021 - Elsevier
Obstructive sleep apnea (OSA) is a common clinical condition associated with increased
cardiovascular morbidity and mortality. Recent evidence from clinical studies and animal …