SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission

MS Kim, CD Froese, MP Estey, WS Trimble - Journal of Cell Biology, 2011 - rupress.org
Septins are filamentous guanosine triphosphatase–binding proteins that are required for
cytokinesis in a wide range of organisms from yeast to man. Several septins, including …

Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission

MP Estey, C Di Ciano-Oliveira, CD Froese… - Journal of cell …, 2010 - rupress.org
Septins are a family of GTP-binding proteins implicated in mammalian cell division. Most
studies examining the role of septins in this process have treated the family as a whole, thus …

Roles of septins in the mammalian cytokinesis machinery

M Kinoshita, M Noda - Cell structure and function, 2001 - jstage.jst.go.jp
Septins comprise a eukaryotic guanine nucleotide binding protein subfamily which form
filamentous heteropolymer complexes. Although mechanism of cytokinesis is diverged by …

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

M Abbey, C Hakim, R Anand, J Lafera, A Schambach… - Scientific reports, 2016 - nature.com
Abstract Septin 7 (SEPT7) has been described to be essential for successful completion of
cytokinesis in mouse fibroblasts and Sept7-deficiency in fibroblasts constitutively results in …

GTP binding and hydrolysis kinetics of human septin 2

YW Huang, MC Surka, D Reynaud… - The FEBS …, 2006 - Wiley Online Library
Septins are a family of conserved proteins that are essential for cytokinesis in a wide range
of organisms including fungi, Drosophila and mammals. In budding yeast, where they were …

Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis

MP Estey, C Di Ciano-Oliveira, CD Froese… - Journal of Biological …, 2013 - ASBMB
Precise cell division is essential for multicellular development, and defects in this process
have been linked to cancer. Septins are a family of proteins that are required for mammalian …

Assembly of mammalian septins

M Kinoshita - Journal of biochemistry, 2003 - academic.oup.com
Septins are a conserved family of polymerizing guanine nucleotide binding proteins
associated with diverse processes in dividing and non-dividing cells. In humans, 12 septin …

Uncovering principles that control septin-septin interactions

MS Kim, CD Froese, H Xie, WS Trimble - Journal of Biological Chemistry, 2012 - ASBMB
Septins comprise a conserved family of GTPases important in cytokinesis. These proteins
polymerize into filaments from rod-shaped heteromeric septin complexes. Septins interact …

Septins: cytoskeletal polymers or signalling GTPases?

CM Field, D Kellogg - Trends in cell biology, 1999 - cell.com
Septins are a family of conserved proteins that have been implicated in a variety of cellular
functions involving specialized regions of the cell cortex and changes in cell shape. The …

Sep (t) arate or not–how some cells take septin-independent routes through cytokinesis

MB Menon, M Gaestel - Journal of cell science, 2015 - journals.biologists.com
Cytokinesis is the final step of cell division, and is a process that requires a precisely
coordinated molecular machinery to fully separate the cytoplasm of the parent cell and to …