What are the benefits of a sustained virologic response to direct-acting antiviral therapy for hepatitis C virus infection?

GN Ioannou, JJ Feld - Gastroenterology, 2019 - Elsevier
Direct-acting antiviral (DAA) regimens are safe and effective at eradicating hepatitis C virus
(HCV) infection. Unfortunately, DAAs remain expensive, so treatment of all HCV-infected …

[PDF][PDF] Direct‐acting antiviral sustained virologic response: impact on mortality in patients without advanced liver disease

LI Backus, PS Belperio, TA Shahoumian, LA Mole - Hepatology, 2018 - Wiley Online Library
The impact of sustained virologic response (SVR) on mortality after direct‐acting antiviral
(DAA) treatment is not well documented in patients without advanced liver disease and …

Disease progression in patients with hepatitis C virus infection treated with direct-acting antiviral agents

M Mendizabal, F Piñero, E Ridruejo, FH Wolff… - Clinical …, 2020 - Elsevier
Background & Aims Little is known about how a sustained virologic response (SVR) to
treatment of hepatitis C virus infection with direct-acting antivirals (DAAs) affects patient …

Effects of a sustained virologic response on outcomes of patients with chronic hepatitis C

V Ng, S Saab - Clinical Gastroenterology and Hepatology, 2011 - Elsevier
For patients with chronic hepatitis C virus infection, the goal of antiviral therapy is to achieve
a sustained virologic response (SVR). We review the durability of the SVR and its effects on …

Long-term treatment outcomes of patients infected with hepatitis C virus: a systematic review and meta-analysis of the survival benefit of achieving a sustained …

B Simmons, J Saleem, K Heath… - Clinical Infectious …, 2015 - academic.oup.com
Background. Achievement of a sustained virologic response (SVR) after treatment for
Hepatitis C infection is associated with improved outcomes. This meta-analysis aimed to …

[HTML][HTML] Achieving sustained virologic response in hepatitis C: a systematic review of the clinical, economic and quality of life benefits

J Smith-Palmer, K Cerri, W Valentine - BMC infectious diseases, 2015 - Springer
Background The goal of chronic hepatitis C treatment is to remove the virus to avoid
progression of HCV-related disease. Sustained virologic response (SVR) is the most widely …

Direct-acting antiviral therapy for hepatitis C virus infection is associated with increased survival in patients with a history of hepatocellular carcinoma

AG Singal, NE Rich, N Mehta, AD Branch, A Pillai… - Gastroenterology, 2019 - Elsevier
Background & Aims There is controversy regarding the benefits of direct-acting antiviral
(DAA) therapy for hepatitis C virus (HCV) infection for patients with a history of …

American Gastroenterological Association Institute Clinical Practice Update—Expert Review: Care of patients who have achieved a sustained virologic response after …

IM Jacobson, JK Lim, MW Fried - Gastroenterology, 2017 - Elsevier
Chronic hepatitis C virus infection is well-recognized as a common blood-borne infection
with global public health impact affecting 3 to 5 million persons in the United States and …

Sustained virologic response to direct-acting antiviral therapy in patients with chronic hepatitis C and hepatocellular carcinoma: a systematic review and meta-analysis

F Ji, YH Yeo, MT Wei, E Ogawa, M Enomoto… - Journal of …, 2019 - Elsevier
Background & Aims The effect of hepatocellular carcinoma (HCC) on the response to
interferon-free direct-acting antiviral (DAA) therapy in patients with chronic hepatitis C (CHC) …

Impact of direct-acting antivirals for HCV on mortality in a large population-based cohort study

NZ Janjua, S Wong, Y Abdia, D Jeong… - Journal of …, 2021 - Elsevier
Background & Aims We evaluated the effect of direct-acting antiviral (DAA)-induced
sustained virologic response (SVR) on all-cause, liver-and drug-related mortality in a …