Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …

Stroke is one of the main causes of mortality and disability in most countries of the world.
The only way of managing patients with ischemic stroke is the use of intravenous tissue …

Stroke is the leading cause of death and adult disability worldwide. Mitochondrial
dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) …

Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

Ischemic stroke is one of the leading causes of death and also a major cause of adult
disability worldwide. Revascularization via reperfusion therapy is currently a standard …

Tissue infarction, involving death of essentially all cells within a part of the brain, is a
common pathology resulting from stroke and an important determinant of the long-term …

Mitochondria play a central role in the pathophysiological processes of acute ischemic
stroke. Disruption of the cerebral blood flow during acute ischemic stroke interrupts oxygen …

Background and Purpose—Stroke is a major cause of death and disability, and it is
imperative to develop therapeutics to mitigate stroke-related injury. Despite many promising …

Stroke is one of the leading causes of death and disability worldwide. Brain injury after
ischemic stroke involves multiple pathophysiological mechanisms, such as oxidative stress …

Evidence obtained over the past two decades shows that reactive oxygen species (ROS) are
involved in brain lesions, including those due to cerebral ischemia-reperfusion. The …