The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica

CF Lucchinetti, Y Guo, BFG Popescu… - Brain …, 2014 - Wiley Online Library
Neuromyelitis optica (NMO) is a disabling autoimmune astrocytopathy characterized by
typically severe and recurrent attacks of optic neuritis and longitudinally extensive myelitis …

Neuromyelitis optica should be classified as an astrocytopathic disease rather than a demyelinating disease

K Fujihara, T Misu, I Nakashima… - Clinical and …, 2012 - Wiley Online Library
Neuromyelitis optica (NMO) is characterized by severe optic neuritis and transverse myelitis.
The relationship of NMO to multiple sclerosis (MS) has long been debated, but NMO has …

Neuromyelitis optica and astrocytic damage in its pathogenesis

K Fujihara - Journal of the neurological sciences, 2011 - Elsevier
Neuromyelitis optica (NMO) is characterized by severe optic neuritis and longitudinally
extended, transverse myelitis. There have been long controversial whether NMO is a variant …

Immunology of neuromyelitis optica: a T cell–B cell collaboration

M Mitsdoerffer, V Kuchroo, T Korn - Annals of the New York …, 2013 - Wiley Online Library
Neuromyelitis optica (NMO) is a debilitating autoimmune inflammatory disease of the central
nervous system (CNS) that is distinct from multiple sclerosis (MS). The discovery of NMO …

A review of the current literature and a guide to the early diagnosis of autoimmune disorders associated with neuromyelitis optica

A Iyer, L Elsone, R Appleton, A Jacob - Autoimmunity, 2014 - Taylor & Francis
Neuromyelitis optica (NMO) is an immune-mediated neurological disorder characterised by
recurrent episodes of optic neuritis and longitudinally extensive transverse myelitis. A serum …

B lymphocytes in neuromyelitis optica

JL Bennett, KC O'Connor, A Bar-Or… - Neuroimmunology & …, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that
predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of …

The immunology of neuromyelitis optica—current knowledge, clinical implications, controversies and future perspectives

M Jasiak-Zatonska, A Kalinowska-Lyszczarz… - International journal of …, 2016 - mdpi.com
Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central
nervous system (CNS) with typical clinical manifestations of optic neuritis and acute …

Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis

SF Roemer, JE Parisi, VA Lennon, EE Benarroch… - Brain, 2007 - academic.oup.com
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that typically affects
optic nerves and spinal cord. Its pathogenic relationship to multiple sclerosis (MS) is …

Neuromyelitis optica: an antibody‐mediated disorder of the central nervous system

J Oh, M Levy - Neurology research international, 2012 - Wiley Online Library
Neuromyelitis optica (NMO) is a recurrent inflammatory disease that preferentially targets the
optic nerves and spinal cord leading to blindness and paralysis. The hallmarks of NMO …

Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica

S Jarius, F Paul, D Franciotta, P Waters… - Nature clinical practice …, 2008 - nature.com
Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …