Background Neoadjuvant chemotherapy for breast cancer was originally used in locally
advanced inoperable disease in order to achieve surgical resection. It was then extended to …

Background Neoadjuvant chemotherapy (NACT) is a standard treatment option for primary
operable breast cancer when adjuvant chemotherapy is indicated. Methods This article …

Primary chemotherapy in localised breast cancer may prevent tumour spread during
surgical treatment and reduce proliferation of micrometastases. A randomised clinical trial, in …

Adjuvant systemic chemotherapy has been shown to prolong survival in all subsets of
patients with breast cancer. In addition, among patients with locally advanced breast cancer …

The use of neoadjuvant chemotherapy in the treatment of breast cancer has been evolving
during the past two decades. Fisher's group accomplished the scientific rationale in mouse …

With advances in science and technology, there are more innovations in the approach to
management of patients with breast cancer. Neoadjuvant chemotherapy that is designed to …

Background Neoadjuvant chemotherapy for early breast cancer can avoid mastectomy by
shrinkage of tumour volume. This review assesses the effectiveness of neoadjuvant …

Neoadjuvant treatment of breast cancer has become established as the safe and often
effective therapeutic approach of choice for larger primary and for locally advanced breast …

BACKGROUND The majority of patients with breast carcinoma receive chemotherapy as a
component of multimodality treatment. Over the past decade, it has become increasingly …

The treatment of breast cancer has evolved from a primary surgical approach with a focus on
local-regional control to multidisciplinary management with an emphasis on systemic …