Estro-progestin contraceptives and risk of cervical cancer: a debated issue

A Gadducci, S Cosio, F Fruzzetti - Anticancer Research, 2020 - ar.iiarjournals.org
Steroid contraceptive hormones may promote human papilloma virus (HPV)-DNA
integration into the host genome, may bind to specific HPV-DNA sequences within …

Hormonal contraception and HPV: a tale of differing and overlapping mechanisms

MA Marks, SL Klein, PE Gravitt - Open Access Journal of …, 2011 - Taylor & Francis
Hormonal contraceptive use is an identified co-factor that modifies cervical cancer risk. The
mechanisms by which sex steroid hormones affect the multi-stage natural history of human …

Cervical cancer and use of hormonal contraceptives: a systematic review

JS Smith, J Green, AB de Gonzalez, P Appleby, J Peto… - The Lancet, 2003 - thelancet.com
Background Human papillomavirus (HPV) is believed to be the most important cause of
cervical cancer. Recent studies suggest that long duration use of oral contraceptives …

Long‐term use of oral contraceptives and risk of invasive cervical cancer

LA Brinton, GR Huggins, HF Lehman… - … journal of cancer, 1986 - Wiley Online Library
To evaluate the relationship between use of oral contraceptives and risk of invasive cervical
cancer, a case‐control study involving 479 patients and 789 population controls was …

Oral contraceptives as risk factors for cervical adenocarcinomas and squamous cell carcinomas

JV Lacey Jr, LA Brinton, FM Abbas, WA Barnes… - … Biomarkers & Prevention, 1999 - AACR
To assess the hypothesis that oral contraceptives (OCs) increase the risk of cervical
adenocarcinomas, we conducted a six-center case-control study of 124 patients with …

The role of steroid contraceptive hormones in the pathogenesis of invasive cervical cancer: a review

M Moodley, J Moodley, R Chetty… - International Journal of …, 2003 - ijgc.bmj.com
Invasive cervical cancer remains a leading cause of morbidity and mortality, especially
among women in the developing world where screening is either deficient or absent. Of all …

Contemporary hormonal contraception and cervical cancer in women of reproductive age

L Iversen, S Fielding, Ø Lidegaard… - … Journal of Cancer, 2021 - Wiley Online Library
To determine cervical cancer risk associated with contemporary hormonal contraceptives,
we conducted a cohort study of women aged 15 to 49 living in Denmark from 1995 to 2014 …

Oral contraceptives are not an independent risk factor for cervical intraepithelial neoplasia or high-risk human papillomavirus infections

K Syrjänen, I Shabalova, N Petrovichev… - Anticancer …, 2006 - ar.iiarjournals.org
Background: Oral contraception (OC) has been proclaimed by the IARC as a risk factor of
cervical cancer (CC), on prolonged use by high-risk human papillomavirus (HPV) positive …

Association between oral contraceptives and cervical cancer: A retrospective case–control study based on the National Health and Nutrition Examination Survey

C Guo, B Zhan, MY Li, L Yue, C Zhang - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: Cervical cancer is the fourth most common cancer among females globally,
with a high incidence and high mortality among females in developing countries. This …

Oral contraceptives, human papillomavirus and cervical cancer

C La Vecchia, S Boccia - European journal of cancer prevention, 2014 - journals.lww.com
Oncogenic human papillomavirus is the key determinant of cervical cancer, but other risk
factors interact with it to define individual risk. Among these, there is oral contraceptive (OC) …