While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …

Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …

Several new findings have emphasized the role of neuron‐specific gap junction proteins
(connexins) and electrical synapses in processing sensory information and in synchronizing …

Stable expression of pannexin 1 (Panx1) and pannexin 3 (Panx3) resulted in functional gap
junctions (GJs) in HeLa cells, but not in Neuro-2a (N2a) or PC-12 cells. The glycosylation …

Pannexins were originally thought to represent a second and redundant family of gap
junction proteins in addition to the well characterized connexins. However, it is now evident …

Coordinated interaction among cells is critical to develop the extremely complex and
dynamic tasks performed by the central nervous system (CNS). Cell synchronization is in …

Functional interaction between neurons and glia is an exciting field that has expanded
tremendously during the past decade. Such partnership has multiple impacts on neuronal …

Pannexins, a class of membrane channels, bear significant sequence homology with the
invertebrate gap junction proteins, innexins, and more distant similarities in their membrane …

Pannexin (Panx) 1 is a widely expressed protein that shares structural, but not amino acid,
homology with gap junction proteins, the connexins. Panx1 does not form gap junctions in …

Connexin hemichannels are single membrane channels which have been traditionally
thought to work in pairs to form gap junction channels across two opposing cells. In …