Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain

TB Cole, J Coburn, K Dao, P Roqué, YC Chang… - Toxicology, 2016 - Elsevier
In addition to increased morbidity and mortality caused by respiratory and cardiovascular
diseases, air pollution may also contribute to central nervous system (CNS) diseases. Traffic …

Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain

ME Gerlofs-Nijland, D van Berlo, FR Cassee… - Particle and fibre …, 2010 - Springer
Background The etiology and progression of neurodegenerative disorders depends on the
interactions between a variety of factors including: aging, environmental exposures, and …

Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone

JL Coburn, TB Cole, KT Dao, LG Costa - Archives of toxicology, 2018 - Springer
Adult neurogenesis is the process by which neural stem cells give rise to new functional
neurons in specific regions of the adult brain, a process that occurs throughout life …

The effect of diesel exhaust exposure on blood–brain barrier integrity and function in a murine model

S Heidari Nejad, R Takechi, BJ Mullins… - Journal of Applied …, 2015 - Wiley Online Library
Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with
vascular‐based disorders. To investigate the effect of DE on blood–brain barrier (BBB) …

Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease

S Levesque, MJ Surace, J McDonald… - Journal of …, 2011 - Springer
Background Increasing evidence links diverse forms of air pollution to neuroinflammation
and neuropathology in both human and animal models, but the effects of long-term …

Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity

S Levesque, T Taetzsch, ME Lull… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Air pollution is linked to central nervous system disease, but the mechanisms
responsible are poorly understood. Objectives: Here, we sought to address the brain-region …

Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study

R Cliff, J Curran, JA Hirota, M Brauer… - Inhalation …, 2016 - Taylor & Francis
Context: Epidemiological studies and animal research have suggested that air pollution may
negatively impact the central nervous system (CNS). Controlled human exposure studies of …

Neurotoxicity of traffic-related air pollution

LG Costa, TB Cole, J Coburn, YC Chang, K Dao… - Neurotoxicology, 2017 - Elsevier
The central nervous system is emerging as an important target for adverse health effects of
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …

Exposure to diesel exhaust during fetal period affects behavior and neurotransmitters in male offspring mice

S Yokota, N Moriya, M Iwata, M Umezawa… - The Journal of …, 2013 - jstage.jst.go.jp
Exposure to ambient particulate matter (PM) has been associated with the onset of
cardiovascular and respiratory diseases. Diesel exhaust particles (DEP) are major …

Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain

D Van Berlo, C Albrecht, AM Knaapen, FR Cassee… - Archives of …, 2010 - Springer
Combustion-derived nanoparticles, such as diesel engine exhaust particles, have been
implicated in the adverse health effects of particulate air pollution. Recent studies suggest …