[HTML][HTML] Oligodendrocyte precursor cells transplantation improves stroke recovery via oligodendrogenesis, neurite growth and synaptogenesis
Ischemic-induced white matter injury is strongly correlated with the poor neurological
outcomes in stroke patients. The transplantation of oligodendrocyte precursor cells (OPCs) …
outcomes in stroke patients. The transplantation of oligodendrocyte precursor cells (OPCs) …
Oligodendrocyte precursor cell transplantation promotes angiogenesis and remyelination via Wnt/β-catenin pathway in a mouse model of middle cerebral artery …
LP Wang, J Pan, Y Li, J Geng, C Liu… - Journal of Cerebral …, 2022 - journals.sagepub.com
White matter injury is a critical pathological characteristic during ischemic stroke.
Oligodendrocyte precursor cells participate in white matter repairing and remodeling during …
Oligodendrocyte precursor cells participate in white matter repairing and remodeling during …
Oligodendrocyte progenitor cell proliferation and fate after white matter stroke in juvenile and adult mice
AL Dingman, KM Rodgers, RM Dietz… - Developmental …, 2019 - karger.com
The incidence of stroke in children is 2.4 per 100,000 person-years and results in long-term
motor and cognitive disability. In ischemic stroke, white matter (WM) is frequently injured, but …
motor and cognitive disability. In ischemic stroke, white matter (WM) is frequently injured, but …
Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral …
X Yu, H Wu, Y Zhao, Y Guo, Y Chen, P Dong, Q Mu… - Brain research, 2018 - Elsevier
The effects of transplanting bone marrow mesenchymal stromal cells (BMSCs) for the
treatment of white matter damage are not well understood, nor are the underlying …
treatment of white matter damage are not well understood, nor are the underlying …
Neural stem/progenitor cells differentiate into oligodendrocytes, reduce inflammation, and ameliorate learning deficits after transplantation in a mouse model of …
The central nervous system has limited capacity for regeneration after traumatic injury.
Transplantation of neural stem/progenitor cells (NPCs) has been proposed as a potential …
Transplantation of neural stem/progenitor cells (NPCs) has been proposed as a potential …
Human neural progenitor cell engraftment increases neurogenesis and microglial recruitment in the brain of rats with stroke
Z Hassani, J O'Reilly, Y Pearse, P Stroemer, E Tang… - PloS one, 2012 - journals.plos.org
Main Objectives Stem cell transplantation is to date one of the most promising therapies for
chronic ischemic stroke. The human conditionally immortalised neural stem cell line …
chronic ischemic stroke. The human conditionally immortalised neural stem cell line …
Conditional ablation of neuroprogenitor cells in adult mice impedes recovery of poststroke cognitive function and reduces synaptic connectivity in the perforant …
C Sun, H Sun, S Wu, CC Lee, Y Akamatsu… - Journal of …, 2013 - Soc Neuroscience
The causal relationship between neurogenesis and the recovery of poststroke cognitive
function has not been properly explored. The current study aimed to determine whether …
function has not been properly explored. The current study aimed to determine whether …
Prolonged myelin deficits contribute to neuron loss and functional impairments after ischaemic stroke
YJ Cheng, F Wang, J Feng, B Yu, B Wang, Q Gao… - Brain, 2024 - academic.oup.com
Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …
effective approaches to preserving neurons and promoting functional recovery remain …
Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke
L Jiang, F Shen, V Degos, M Schonemann… - Translational stroke …, 2011 - Springer
Oligogenesis plays an important role in functional recovery after ischemic stroke. We tested
the hypothesis that oligogenesis and the maturation of oligodendrocyte progenitor cells …
the hypothesis that oligogenesis and the maturation of oligodendrocyte progenitor cells …
cxcl12 gene engineered endothelial progenitor cells further improve the functions of oligodendrocyte precursor cells
Oligodendrocyte precursor cells (OPCs) are needed for white matter repair after various
brain injury. Means that promote OPC functions could benefit white matter recovery after …
brain injury. Means that promote OPC functions could benefit white matter recovery after …