MATERIALS AND METHODS L-Alanine dehydrogenase(EC 1.4. 1.1.), L-glutamate
dehydrogenase (EC 1.4. 1.3.), and beef heart L-lactate dehydrogenase(EC 1.1. 1.27). as a …

Protein synthesis in heart muscle has been studied in the isolated rat heart perfused with
buffer containing glucose and various amino acid mixtures. The rate of synthesis was …

Perfusion of the isolated rat heart under anaerobic conditions inhibited synthesis of whole
heart protein and myosin. The effect was reversible and did not appear to be due to the …

The inclusion of plasma levels of the natural amino acids plus 2.5 mM glutamate and 2.5 mM
malate (PAAGM) raised the oxygen consumption and glucose oxidation of isolated cardiac …

De novo synthesis of adenine nucleotides was measured in rat hearts in situ and in isolated
perfused rat hearts under normal conditions and during recovery from asphyxia or ischemia …

In oxygen-deprived heart muscle tissue, alanine levels increase, whereas levels of
glutamate and aspartate decline, and it is therefore postulated that free tissue amino acids …

Since skeletal muscle is the major site in the body for oxidation of leucine, isoleucine and
valine, the pathway and control of leucine oxidation were investigated in cell-free …

ATP and 5′-AMP were extensively degraded to adenosine and inosine during a single
passage through rat hearts perfused in an open-flow system. It is suggested that enzymes …

1. Rat heart perfused with Krebs-Henseleit bicarbonate buffer released material containing
ninhydrin-positive nitrogen, but the amount was less than that reported to be released by …

Alanine production and pyruvate content of the isolated rat hemidiaphragm are increased by
isoleucine or glutamate. These results support the hypothesis that amino acids are …