Immunogenicity of a contiguous TB synthetic epitope of the A/PR/8/34 influenza virus

TD Brumeanu, S Casares, A Bot, S Bot… - Journal of virology, 1997 - Am Soc Microbiol
A contiguously linked TB synthetic viral epitope (110HA120-150HA159, TB) was
investigated for its potency in inducing humoral and cellular immune responses in vivo. The …

Protection of mice against lethal viral infection by synthetic peptides corresponding to B-and T-cell recognition sites of influenza A hemagglutinin

J Simeckova-Rosenberg, Z Yun, PR Wyde, MZ Atassi - Vaccine, 1995 - Elsevier
Previously, we reported 12 synthetic T-and B-cell recognition regions representing surface
areas of the hemagglutinin (HA) of X31 influenza virus. In the present study, four of these …

A Human CD4+ T Cell Epitope in the Influenza Hemagglutinin Is Cross-Reactive to Influenza A Virus Subtypes and to Influenza B Virus

JAB Babon, J Cruz, FA Ennis, L Yin… - Journal of virology, 2012 - Am Soc Microbiol
The hemagglutinin protein (HA) of the influenza virus family is a major antigen for protective
immunity. Thus, it is a relevant target for developing vaccines. Here, we describe a human …

Identification and characterization of T helper epitopes in the nucleoprotein of influenza A virus.

XM Gao, FY Liew, JP Tite - Journal of immunology (Baltimore, Md …, 1989 - journals.aai.org
By using a series of overlapping synthetic peptides that cover more than 95% of the amino
acid sequence of nucleoprotein (NP) of influenza A/NT/60/68 virus, five Th cell epitopes in …

Immunogenicity of free synthetic peptides corresponding to T helper epitopes of the influenza HA 1 subunit: Induction of virus cross reacting CD 4+ T lymphocytes in …

C Schneider, MHV Van Regenmortel - Archives of virology, 1992 - Springer
Four linear synthetic peptides corresponding to residues 12–29, 50–67, 121–138 and 131–
147 of the HA 1 subunit of H 3 subtype influenza virus (NT/60/68) were tested for their …

Class II-restricted T-cell clones to a synthetic peptide of influenza virus hemagglutinin differ in their fine specificities and in the ability to respond to virus

RA Ffrench, XL Tang, EM Anders, DC Jackson… - Journal of …, 1989 - Am Soc Microbiol
Fifteen T-cell clones were derived from BALB/c or DBA/2 mice immunized with a synthetic
peptide corresponding to the C-terminal 24 residues (residues 305 to 328) of the HA1 chain …

A synthetic decapeptide of influenza virus hemagglutinin elicits helper T cells with the same fine recognition specificities as occur in response to whole virus.

CJ Hackett, JL Hurwitz, B Dietzschold… - Journal of immunology …, 1985 - journals.aai.org
The immunogenicity of an isolated murine helper T cell determinant was studied. Mice were
immunized with a synthetic peptide corresponding to amino acid residues 111-120 of the …

Definition of amino acid residues on the epitope responsible for recognition by influenza A virus H1-specific, H2-specific, and H1-and H2-cross-reactive murine …

M Tamura, K Kuwano, I Kurane, FA Ennis - Journal of virology, 1998 - Am Soc Microbiol
We defined the epitopes recognized by three influenza A virus-specific, H-2Kd-restricted
CD8+ cytotoxic T-lymphocyte (CTL) clones: H1-specific clone A-12, H2-specific clone F-4 …

Distinct epitopes recognized by I-Ad-restricted T-cell clones within antigenic site E on influenza virus hemagglutinin

LE Brown, RA Ffrench, JM Gawler, DC Jackson… - Journal of …, 1988 - Am Soc Microbiol
A total of 14 I-Ad-restricted helper T-cell clones specific for the hemagglutinin (HA) molecule
of influenza virus were isolated from spleens of BALB/c or (BALB/c X C57BL/10) F1 mice …

Identification of eight determinants in the hemagglutinin molecule of influenza virus A/PR/8/34 (H1N1) which are recognized by class II-restricted T cells from BALB/c …

W Gerhard, AM Haberman, PA Scherle… - Journal of …, 1991 - Am Soc Microbiol
Eight nonoverlapping regions of the hemagglutinin (HA) molecule of influenza virus
A/PR/8/34 (PR8), which serve as recognition sites for class II-restricted T cells (TH) from …