The discovery of cell-free fetal DNA (cffDNA) in maternal plasma has enabled a paradigm
shift in prenatal testing, allowing for safer, earlier detection of genetic conditions of the fetus …

Fetal aneuploidies are among the most common causes of miscarriages, perinatal mortality
and neurodevelopmental impairment. During the last 70 years, many efforts have been …

The recent release of new, non-invasive prenatal tests for fetal aneuploidy using cell-free
fetal DNA (cffDNA) has been hailed as a revolution in prenatal testing and has triggered …

Non-invasive prenatal testing (NIPT) through the analysis of cell free (cf) DNA is
revolutionizing prenatal screening for fetal aneuploidy. Current methods used in clinical …

Highlights•Cell free DNA–the biological basis and the sequencing techniques behind
NIPT.•Clinical performance of NIPT for the common automosomal trisomies and …

The discovery of cell free fetal DNA in maternal plasma has stimulated a rapid development
of non-invasive prenatal testing. The recent advent of massively parallel sequencing has …

Noninvasive prenatal diagnosis using cell-free fetal DNA in the maternal plasma is moving
into routine clinical practice for some indications. Here we discuss exciting developments in …

Non‐invasive prenatal testing (NIPT) for fetal aneuploidy detection is increasingly being
offered in the clinical setting. Whereas the majority of tests only report fetal trisomies 21, 18 …

Non invasive prenatal Testing (NIPT) is changing the practice of prenatal diagnosis
worldwide. It provides high sensitivity and specificity in screening for common aneuploidies …

Cell-free DNA (cfDNA) testing has recently become indispensable in diagnostic testing and
screening. In the prenatal setting, this type of testing is often called noninvasive prenatal …