Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …

Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

While bone tissue is known for its inherent regenerative abilities, various pathological
conditions and trauma can disrupt its meticulously regulated processes of bone formation …

In recent years, bone regeneration has emerged as a remarkable field that offers promising
guidance for treating bone-related diseases, such as bone defects, bone infections, and …

The treatment of bone defects is an important problem in clinical practice. The rapid
development of bone tissue engineering (BTE) may provide a new method for bone defect …

Conventional grafting techniques for bone regeneration are currently being replaced by
tissue engineering approaches of using 3D biomimetic materials. Of these biomaterials …

Magnesium (Mg)-based implants have become of interest to both academia and the medical
industry. The attraction largely is due to Mg's biodegradability and ability to enhance bone …

Zinc has been described as the 'calcium of the twenty-first century'. Zinc-based degradable
biomaterials have recently emerged thanks to their intrinsic physiological relevance …

Zinc is an essential mineral that is required for normal skeletal growth and bone
homeostasis. Furthermore, zinc appears to be able to promote bone regeneration. However …

The election of bone tissue engineering scaffolds material is mainly based on the bionics of
natural bones. Although the content of trace elements in bone is low, the lack of them affects …