An anti-fibroblast adhesion and anti-inflammatory hydrogel film combined with VEGF for intrauterine adhesion prevention

X Liu, H Wang, J She, Q Zhang, Q Hu, D Li… - Chemical Engineering …, 2023 - Elsevier
Intrauterine adhesions (IUA) are a common gynecologic disease worldwide that can lead to
menstrual irregularities, infertility, or repeated pregnancy loss. Biomaterials are used as a …

Application of bioactive hydrogels for functional treatment of intrauterine adhesion

J Wang, C Yang, Y Xie, X Chen, T Jiang… - … in Bioengineering and …, 2021 - frontiersin.org
Intrauterine adhesion (IUA) is a common endometrial disease and one of the main causes of
infertility in women of childbearing age. Current treatment strategies, such as hysteroscopic …

Antifouling and injectable granular hydrogel for the prevention of postoperative intrauterine adhesion

W Xia, Q Wang, M Liu, S Lu, H Yu, H Yin… - … Applied Materials & …, 2023 - ACS Publications
Postoperative intrauterine adhesion (IUA), caused by endometrial basal layer injury, is one
of the main causes of female infertility. The excessive deposition of fibrin as well as fibroblast …

Hydrogel, a novel therapeutic and delivery strategy, in the treatment of intrauterine adhesions

H Lv, B Wu, J Song, W Wu, W Cai, J Xu - Journal of Materials Chemistry …, 2021 - pubs.rsc.org
Intrauterine adhesions (IUAs) are caused by damage to the underlying lining of the
endometrium. They're related to disorder of endometrial repair. In recent years, hydrogels …

Temperature-sensitive heparin-modified poloxamer hydrogel with affinity to KGF facilitate the morphologic and functional recovery of the injured rat uterus

HL Xu, J Xu, SS Zhang, QY Zhu, BH Jin, DL ZhuGe… - Drug Delivery, 2017 - Taylor & Francis
Endometrial injury usually results in intrauterine adhesion (IUA), which is an important cause
of infertility and recurrent miscarriage in reproductive women. There is still lack of an …

Amorphous curcumin-based hydrogels to reduce the incidence of post-surgical intrauterine adhesions

W Zhang, Y He, Y Chu, Y Zhai, S Qian… - Regenerative …, 2024 - academic.oup.com
The incidence of intrauterine adhesions (IUA) was raised accompanied by the increasing
utilization of intrauterine surgery. The postoperative physical barrier methods commonly …

[HTML][HTML] Engineering self-healing adhesive hydrogels with antioxidant properties for intrauterine adhesion prevention

L Feng, L Wang, Y Ma, W Duan, S Martin-Saldaña… - Bioactive materials, 2023 - Elsevier
Intrauterine adhesion (IUA) is the fibrosis within the uterine cavity. It is the second most
common cause of female infertility, significantly affecting women's physical and mental …

Three-dimensional structure micelles of heparin-poloxamer improve the therapeutic effect of 17β-estradiol on endometrial regeneration for intrauterine adhesions in a …

SS Zhang, WT Xia, J Xu, HL Xu, CT Lu… - International journal …, 2017 - Taylor & Francis
Intrauterine adhesions (IUA) frequently occur after infectious or mechanical injury to the
endometrium, which may lead to infertility and/or pregnancy complications. There are few …

A mechanically robust and stable estradiol-loaded PHEMA-based hydrogel barrier for intrauterine adhesion treatment

X Xie, R Xu, H Ouyang, S Tan, C Guo, X Luo… - Journal of Materials …, 2022 - pubs.rsc.org
Estrogen combined with physical barrier therapy may be a prospective method to repair a
damaged endometrium and prevent postsurgical re-adhesion in the treatment of intrauterine …

Recent developments in biomaterial-based hydrogel as the delivery system for repairing endometrial injury

G Cai, Z Hou, W Sun, P Li, J Zhang, L Yang… - … in Bioengineering and …, 2022 - frontiersin.org
Endometrial injury caused by intrauterine surgery often leads to pathophysiological changes
in the intrauterine environment, resulting in infertility in women of childbearing age …