[HTML][HTML] The evolution of therapies in non-small cell lung cancer

V Boolell, M Alamgeer, DN Watkins, V Ganju - Cancers, 2015 - mdpi.com
The landscape of advanced non-small lung cancer (NSCLC) therapies has rapidly been
evolving beyond chemotherapy over the last few years. The discovery of oncogenic driver …

New targets for non-small-cell lung cancer therapy

M Alvarez, E Roman, ES Santos… - Expert review of …, 2007 - Taylor & Francis
Lung cancer remains the leading cause of malignancy-related deaths in the USA,
regardless of advances in therapeutic agents. Non-small-cell lung cancer demonstrates …

[HTML][HTML] Non-small-cell lung cancer: New rare targets—New targeted therapies—state of the art and future directions

K Stencel, I Chmielewska, J Milanowski, R Ramlau - Cancers, 2021 - mdpi.com
Simple Summary The use of novel therapeutic drugs in lung cancer has changed the
paradigm of the diagnosis and treatment of lung cancer. Due to the development of …

Molecular testing and targeted therapy for non-small cell lung cancer: current status and perspectives

EN Imyanitov, AG Iyevleva, EV Levchenko - Critical reviews in oncology …, 2021 - Elsevier
Molecular testing has become a mandatory component of the non-small cell lung cancer
(NSCLC) management. The detection of EGFR, BRAF and MET mutations as well as the …

Treatment of non-small-cell lung cancer: state of the art and development of new biologic agents

C Gridelli, A Rossi, P Maione - Oncogene, 2003 - nature.com
Conventional treatment of non-small-cell lung cancer (NSCLC) has apparently reached a
plateau of effectiveness in improving the survival of NSCLC patients. Although neoadjuvant …

Shortcomings of current therapies for non-small-cell lung cancer: unmet medical needs

HA Burris - Oncogene, 2009 - nature.com
Non-small-cell lung cancer (NSCLC) is a major global health problem and is the leading
cause of cancer death worldwide. Current treatment involves nonspecific, nonselective …

[HTML][HTML] Emerging targeted therapies in advanced non-small-cell lung cancer

S Li, GS de Camargo Correia, J Wang, R Manochakian… - Cancers, 2023 - mdpi.com
Simple Summary The discovery of actionable oncogenic driver mutations in non-small-cell
lung cancer (NSCLC) has revolutionized the treatment and prognosis of this dreadful …

The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer

B Melosky, P Wheatley-Price, RA Juergens, A Sacher… - Lung Cancer, 2021 - Elsevier
Lung cancer is a highly heterogeneous disease often driven by well-characterized driver
mutations. Although the best studied are common alterations in the epidermal growth factor …

[HTML][HTML] Review of the current targeted therapies for non-small-cell lung cancer

KSH Nguyen, JW Neal, H Wakelee - World journal of clinical …, 2014 - ncbi.nlm.nih.gov
The last decade has witnessed the development of oncogene-directed targeted therapies
that have significantly changed the treatment of non-small-cell lung cancer (NSCLC). In this …

[HTML][HTML] Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer

P Savas, B Hughes, B Solomon - Journal of Thoracic Disease, 2013 - ncbi.nlm.nih.gov
Advances in the treatment of non-small cell lung cancer (NSCLC) over the last decade have
predominantly involved the development of therapies directed at molecular targets such as …