A double-edged sword: focusing on potential drug-to-drug interactions of quercetin

K Ding, H Jia, W Jiang, Y Qin, Y Wang, M Lei - Revista Brasileira de …, 2023 - Springer
Herbal and herbal dietary supplements have a massive share of the global market, and their
use continues to grow worldwide. There is a general perception that herbal and herbal …

Quercetin: The biological effects, chemical steadiness, metabolism, and delivery systems

R Sobhy, I Khalifa, A Rahaman, XA Zeng… - Handbook of dietary …, 2023 - Springer
One of the most well-known flavonoids, quercetin, has long been a part of the human diet.
Numerous health advantages, including antioxidant, anti-inflammatory, antiviral, and …

Enhancing the potential preclinical and clinical benefits of quercetin through novel drug delivery systems

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Drug discovery today, 2020 - Elsevier
Highlights•Pharmacological activities and molecular targets of quercetin.•Mechanistic
pathways of quercetin for treating different diseases.•Formulation strategies for improving …

[PDF][PDF] Approaches and Advancements in the Improvement of Quercetin Bioavailability

AP Chaithanya, R Saravanan, V Sebastin… - 2024 - researchgate.net
Quercetin is a plant derived aglycone form of flavonoid glycosides. It has nutritional value
and well known for its diverse biological activities such as anticancer, antiulcer …

Bioavailability of quercetin: problems and promises

X Cai, Z Fang, J Dou, A Yu… - Current medicinal …, 2013 - ingentaconnect.com
Quercetin (QC) is a typical plant flavonoid, possesses diverse pharmacologic effects
including antiinflammatory, antioxidant, anti-cancer, anti-anaphylaxis effects and against …

The biological activities, chemical stability, metabolism and delivery systems of quercetin: A review

W Wang, C Sun, L Mao, P Ma, F Liu, J Yang… - Trends in food science & …, 2016 - Elsevier
Background Quercetin, one of the most well-known flavonoids, has been included in human
diet for a long history. The use of quercetin has been widely associated with a great number …

Safety aspects of the use of quercetin as a dietary supplement

S Andres, S Pevny, R Ziegenhagen… - Molecular nutrition & …, 2018 - Wiley Online Library
The flavonoid quercetin is frequently found in low amounts as a secondary plant metabolite
in fruits and vegetables. Isolated quercetin is also marketed as a dietary supplement, mostly …

Pharmacokinetics and modeling of quercetin and metabolites

X Chen, OQP Yin, Z Zuo, MSS Chow - Pharmaceutical research, 2005 - Springer
Purpose To determine the pharmacokinetics of quercetin and its glucuronide/sulfate
conjugates and to develop a pharmacokinetic model to simultaneously describe their …

Intestinal disposition of quercetin and its phase-II metabolites after oral administration in healthy volunteers

C Chalet, J Rubbens, J Tack… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives Quercetin is one of the main dietary flavonoids and undergoes a substantial
intestinal phase-II metabolism. Quercetin conjugates have been detected in plasma and in …

A review of various pharmacological effects of quercetin with its barriers and approaches for solubility and permeability enhancement

R Mishra, S Kulkarni - The Natural Products Journal, 2022 - ingentaconnect.com
Background: Quercetin, one of the most beneficial flavonoids, has been included in the
human diet due to its therapeutic effect on health. Recently, quercetin has been gaining …