[HTML][HTML] Genetically engineered bacterium: Principles, practices, and prospects
Y Liu, J Feng, H Pan, X Zhang, Y Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
Advances in synthetic biology and the clinical application of bacteriotherapy enable the use
of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small …
of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small …
Genetically engineered bacteria: a new frontier in targeted drug delivery
Genetically engineered bacteria (GEB) have shown significant promises to revolutionize
modern medicine. These engineered bacteria with unique properties such as enhanced …
modern medicine. These engineered bacteria with unique properties such as enhanced …
Engineered bacteria as therapeutic agents
C Piñero-Lambea, D Ruano-Gallego… - Current opinion in …, 2015 - Elsevier
Highlights•Engineered bacteria provide a continuous supply of therapeutic
molecules.•Bacterial therapies target inflammation, immunity, cancer, and metabolic …
molecules.•Bacterial therapies target inflammation, immunity, cancer, and metabolic …
Bacterially mediated drug delivery and therapeutics: strategies and advancements
L Wu, F Bao, L Li, X Yin, Z Hua - Advanced drug delivery reviews, 2022 - Elsevier
It was already clinically apparent 150 years ago that bacterial therapy could alleviate
diseases. Recently, a burgeoning number of researchers have been using bacterial …
diseases. Recently, a burgeoning number of researchers have been using bacterial …
Bioengineered microbes in disease therapy
Naturally occurring microorganisms have been used therapeutically for over a century, but
the advent of modern techniques for genetic manipulation has created unprecedented …
the advent of modern techniques for genetic manipulation has created unprecedented …
Reprogrammable microbial cell-based therapeutics against antibiotic-resistant bacteria
The discovery of antimicrobial drugs and their subsequent use has offered an effective
treatment option for bacterial infections, reducing morbidity and mortality over the past 60 …
treatment option for bacterial infections, reducing morbidity and mortality over the past 60 …
Engineered bacteria in tumor immunotherapy
H Chen, Y Zhu, C Zhang, L Hu, K Yang - Cancer Letters, 2024 - Elsevier
As the limitations of cancer immunotherapy become increasingly apparent, there is
considerable anticipation regarding the utilization of biological tools to enhance treatment …
considerable anticipation regarding the utilization of biological tools to enhance treatment …
[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …
evidence showing that new types of biotherapy using engineered bacterial therapeutics …
Bacteria-driven bio-therapy: From fundamental studies to clinical trials
Y Yu, S Lin, Z Chen, B Qin, Z He, M Cheng, M Sun… - Nano Today, 2023 - Elsevier
Natural bacteria have been utilized to directly maintain the human body's homeostasis for
directly or indirectly relieving diseases throughout history. With the rapid development of …
directly or indirectly relieving diseases throughout history. With the rapid development of …
[PDF][PDF] Bacterial vectors and delivery systems in cancer therapy
R Gardlik, JH Fruehauf - IDrugs, 2010 - researchgate.net
Live bacterial vectors may be useful tools for the development of novel cancer therapies that
can be added to the repertoire of existing drugs. Several bacterial strains effectively colonize …
can be added to the repertoire of existing drugs. Several bacterial strains effectively colonize …