[HTML][HTML] Genetically engineered bacterium: Principles, practices, and prospects

Y Liu, J Feng, H Pan, X Zhang, Y Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
Advances in synthetic biology and the clinical application of bacteriotherapy enable the use
of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small …

Genetically engineered bacteria: a new frontier in targeted drug delivery

S Fooladi, N Rabiee, S Iravani - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Genetically engineered bacteria (GEB) have shown significant promises to revolutionize
modern medicine. These engineered bacteria with unique properties such as enhanced …

Engineered bacteria as therapeutic agents

C Piñero-Lambea, D Ruano-Gallego… - Current opinion in …, 2015 - Elsevier
Highlights•Engineered bacteria provide a continuous supply of therapeutic
molecules.•Bacterial therapies target inflammation, immunity, cancer, and metabolic …

Bacterially mediated drug delivery and therapeutics: strategies and advancements

L Wu, F Bao, L Li, X Yin, Z Hua - Advanced drug delivery reviews, 2022 - Elsevier
It was already clinically apparent 150 years ago that bacterial therapy could alleviate
diseases. Recently, a burgeoning number of researchers have been using bacterial …

Bioengineered microbes in disease therapy

AW Paton, R Morona, JC Paton - Trends in molecular medicine, 2012 - cell.com
Naturally occurring microorganisms have been used therapeutically for over a century, but
the advent of modern techniques for genetic manipulation has created unprecedented …

Reprogrammable microbial cell-based therapeutics against antibiotic-resistant bacteria

IY Hwang, E Koh, HR Kim, WS Yew… - Drug Resistance Updates, 2016 - Elsevier
The discovery of antimicrobial drugs and their subsequent use has offered an effective
treatment option for bacterial infections, reducing morbidity and mortality over the past 60 …

Engineered bacteria in tumor immunotherapy

H Chen, Y Zhu, C Zhang, L Hu, K Yang - Cancer Letters, 2024 - Elsevier
As the limitations of cancer immunotherapy become increasingly apparent, there is
considerable anticipation regarding the utilization of biological tools to enhance treatment …

[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy

SR Kang, DH Nguyen, SW Yoo, JJ Min - Advanced Drug Delivery Reviews, 2022 - Elsevier
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …

Bacteria-driven bio-therapy: From fundamental studies to clinical trials

Y Yu, S Lin, Z Chen, B Qin, Z He, M Cheng, M Sun… - Nano Today, 2023 - Elsevier
Natural bacteria have been utilized to directly maintain the human body's homeostasis for
directly or indirectly relieving diseases throughout history. With the rapid development of …

[PDF][PDF] Bacterial vectors and delivery systems in cancer therapy

R Gardlik, JH Fruehauf - IDrugs, 2010 - researchgate.net
Live bacterial vectors may be useful tools for the development of novel cancer therapies that
can be added to the repertoire of existing drugs. Several bacterial strains effectively colonize …