Statins and dietary modifications are the cornerstone of hypercholesterolemia management.
Although it is well known that possible adverse effect of statins can occur due to drug-drug …

Concomitant administration of statins with food may alter statin pharmacokinetics or
pharmacodynamics, increasing the risk of adverse reactions such as myopathy or …

hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors, statins, are a
primary treatment for hyperlipidemic cardiovascular diseases which are a leading global …

Hypercholesterolemia constitutes one of the main cardiovascular risk factors and,
consequently, treat it is really important to limit the risk of one of the leading causes of death …

Background and Aim Green tea and soy products are extensively consumed in daily life.
Research has shown that green tea catechins and soy isoflavones may influence the activity …

Dyslipidaemia accelerates the atherosclerotic process and its morbid consequences; statins
represent the evidence-based treatment of choice for reducing low-density lipoprotein …

Several risk factors such as abnormality of lipid metabolism (eg high levels of low-density
lipoprotein cholesterol (LDL-C), elevated triglycerides and low levels of high-density …

AIM:: Dietary cholesterol absorption, endogenous cholesterol synthesis and biliary
cholesterol excretion regulate whole body cholesterol balance as a result of …

Cardiovascular disease remains the leading cause of morbidity and mortality in the United
States and other developed countries, and is fast growing in developing countries …

Background Simvastatin is a cholesterol‐lowering agent that is metabolized through
CYP3A4. We studied the effect of grapefruit juice on the pharmacokinetics of orally …