[HTML][HTML] Polyunsaturated fatty acid metabolism in the brain and brain cells

C Joffre - Feed your mind-How does nutrition modulate brain …, 2019 - intechopen.com
Dietary polyunsaturated fatty acids (PUFAs) have gained more importance these last
decades since they regulate the level of long-chain PUFAs (LC-PUFAs) in all cells and …

N-3 polyunsaturated fatty acids and the resolution of neuroinflammation

C Joffre, C Rey, S Layé - Frontiers in pharmacology, 2019 - frontiersin.org
In the past few decades, as a result of their anti-inflammatory properties, n-3 long chain
polyunsaturated fatty acids (n-3 LC-PUFAs), have gained greater importance in the …

Polyunsaturated fatty acids and their metabolites in brain function and disease

RP Bazinet, S Layé - Nature reviews neuroscience, 2014 - nature.com
The brain is highly enriched with fatty acids. These include the polyunsaturated fatty acids
(PUFAs) arachidonic acid and docosahexaenoic acid, which are largely esterified to the …

N-3 polyunsaturated fatty acids and their derivates reduce neuroinflammation during aging

C Joffre, AL Dinel, M Chataigner, V Pallet, S Layé - Nutrients, 2020 - mdpi.com
Aging is associated to cognitive decline, which can lead to loss of life quality, personal
suffering, and ultimately neurodegenerative diseases. Neuroinflammation is one of the …

Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology

S Laye, A Nadjar, C Joffre, RP Bazinet - Pharmacological reviews, 2018 - ASPET
Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Role of polyunsaturated fatty acids and their metabolites on stem cell proliferation and differentiation

MA Rashid, M Haque, M Akbar - The Benefits of Natural Products for …, 2016 - Springer
The nervous system is highly enriched with long-chain polyunsaturated fatty acids (PUFAs).
Essential fatty acids, namely, ω-6 (n− 6) and ω-3 (n− 3) PUFA, and their metabolites are …

n-3 Polyunsaturated fatty acids in animal models with neuroinflammation

SK Orr, MO Trépanier, RP Bazinet - Prostaglandins, Leukotrienes and …, 2013 - Elsevier
Neuroinflammation is present in the majority of acute and chronic neurological disorders.
Excess or prolonged inflammation in the brain is thought to exacerbate neuronal damage …

Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease

JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

[HTML][HTML] Role of polyunsaturated fatty acids in ischemic stroke–A perspective of specialized pro-resolving mediators

Z Miao, M Schultzberg, X Wang, Y Zhao - Clinical Nutrition, 2021 - Elsevier
Polyunsaturated fatty acids (PUFAs) have been proposed as beneficial for cardiovascular
health. However, results from both epidemiological studies and clinical trials have been …

Role of omega-3 PUFAs in neurobiological health

R Grant, J Guest - The Benefits of Natural Products for …, 2016 - Springer
The importance of the essential, dietary-derived, polyunsaturated fatty acids (PUFAs) omega-
6 and omega-3 to human health was first reported over 85 years ago. Subsequent research …