The cornea serves as an important barrier structure to the eyeball and is vulnerable to
injuries, which may lead to scarring and blindness if not treated promptly. To explore an …

The dome-shaped cornea is a transparent, non-vascularized, and epithelialized highly
organized tissue. Physical and chemical injuries may trigger corneal wound healing (CWH) …

Limbal stem cells (LSC) maintain the transparency of the corneal epithelium. Chemical
burns lead the loss of LSC inducing an up‐regulation of pro‐inflammatory and pro …

Corneal chemical burns can lead to blindness following serious complications. As most of
these complications are caused by failure of reepithelization during the acute phase …

Utilizing tissue-specific extracellular matrices (ECMs) is vital for replicating the composition
of native tissues and developing biologically relevant biomaterials. Human-or animal …

Purpose: Mesenchymal stem cells (MSCs) have been extensively studied for their capacity
to enhance wound healing and represent a promising research field for generating cell …

The aim of our study was to assess the clinical effectiveness of topical adipose derived stem
cell (ADSC) treatment in laser induced corneal wounds in mice by comparing epithelial …

Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction,
recurrent erosions, and keratitis. Adenoviral gene therapy modulating c-Met, cathepsin F …

Dry eye syndrome (DES) is a chronic ocular disease that induces epithelial damage to the
cornea by decreasing tear production and quality. Adequate treatment options have not …

Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring
and stimulate regeneration of transparent stromal tissue after corneal wounding in mice …