Celecoxib modulates adhesion of HT29 colon cancer cells to vascular endothelial cells by inhibiting ICAM‐1 and VCAM‐1 expression
C Dianzani, L Brucato, M Gallicchio… - British journal of …, 2008 - Wiley Online Library
Background and purpose: Cyclooxygenase‐2 (COX‐2) is highly expressed during
inflammation and can promote the progression of colorectal cancer. Interactions between …
inflammation and can promote the progression of colorectal cancer. Interactions between …
Celecoxib decreases expression of the adhesion molecules ICAM‐1 and VCAM‐1 in a colon cancer cell line (HT29)
M Gallicchio, AC Rosa, C Dianzani… - British journal of …, 2008 - Wiley Online Library
Background and purpose: We investigated the ability of celecoxib, a selective
cyclooxygenase‐2 (COX‐2) inhibitor, to modulate expression of ICAM‐1 and VCAM‐1 in the …
cyclooxygenase‐2 (COX‐2) inhibitor, to modulate expression of ICAM‐1 and VCAM‐1 in the …
Selective inhibition of cyclooxygenase‐2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of β1 integrin
K Yazawa, NH Tsuno, J Kitayama, K Kawai… - Cancer …, 2005 - Wiley Online Library
High level expression of cyclooxygenase (COX)‐2 is reported in 80–90% of colorectal
adenocarcinomas. In the recent years, selective inhibitors of COX‐2 have been developed …
adenocarcinomas. In the recent years, selective inhibitors of COX‐2 have been developed …
PC‐407, a celecoxib derivative, inhibited the growth of colorectal tumor in vitro and in vivo
Y Li, Y Niu, H Wu, B Zhang, Y Sun, H Huang… - Cancer …, 2009 - Wiley Online Library
This study aimed to observe the growth‐inhibitory effect of PC‐407 (4‐[5‐naphthyl‐3‐
(trifluoromethyl)‐1H‐pyrazol‐1‐yl] benzenesulfonamide), a celecoxib derivative synthesized …
(trifluoromethyl)‐1H‐pyrazol‐1‐yl] benzenesulfonamide), a celecoxib derivative synthesized …
Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells
S Lev-Ari, L Strier, D Kazanov, L Madar-Shapiro… - Clinical Cancer …, 2005 - AACR
Purpose: Multiple studies have indicated that cyclooxygenase-2 (COX-2) inhibitors may
prevent colon cancer, which is one of the leading causes of cancer death in the western …
prevent colon cancer, which is one of the leading causes of cancer death in the western …
Celecoxib inactivates epithelial–mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells
C Bocca, F Bozzo, S Cannito, M Parola… - Molecular …, 2012 - Wiley Online Library
Abstract Celecoxib, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has been reported to
exert chemopreventive and antitumor effects on colon cancer, one of the most common solid …
exert chemopreventive and antitumor effects on colon cancer, one of the most common solid …
[HTML][HTML] Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer
P de Heer, MH Sandel, G Guertens, G de Boeck… - Cancer chemotherapy …, 2008 - Springer
Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce the
risk of colorectal cancer in cyclooxygenase-2 (COX-2) overexpressing colorectal cancers …
risk of colorectal cancer in cyclooxygenase-2 (COX-2) overexpressing colorectal cancers …
[HTML][HTML] Celecoxib increases lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1
M Schellhorn, M Haustein, M Frank, M Linnebacher… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The antitumorigenic mechanism of the selective cyclooxygenase-2 (COX-2) inhibitor
celecoxib is still a matter of debate. Using lung cancer cell lines (A549, H460) and metastatic …
celecoxib is still a matter of debate. Using lung cancer cell lines (A549, H460) and metastatic …
Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas
I Casanova, M Parreno, L Farré… - … journal of cancer, 2006 - Wiley Online Library
Abstract Celecoxib, a selective cyclooxygenase‐2 (COX‐2) inhibitor, is effective as
chemopreventive against colon cancer and it is the only nonsteoroidal antiinflammatory drug …
chemopreventive against colon cancer and it is the only nonsteoroidal antiinflammatory drug …
[HTML][HTML] Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum
I Ninomiya, N Nagai, K Oyama… - Oncology …, 2012 - spandidos-publications.com
We examined the effects of the preferential cyclooxygenase-2 (COX-2) inhibitor celecoxib on
tumorigenesis, angiogenesis, apoptosis, vascular endothelial growth factor (VEGF) protein …
tumorigenesis, angiogenesis, apoptosis, vascular endothelial growth factor (VEGF) protein …