Nucleosides having bicyclic sugar moiety
G Wang - US Patent 6,403,566, 2002 - Google Patents
BACKGROUND Nucleoside and nucleotide analogs have long been used as
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …
Nucleosides having bicyclic sugar moiety
Z Hong, H An - US Patent 6,833,361, 2004 - Google Patents
BACKGROUND Nucleoside and nucleotide analogs have long been used as
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …
Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates
C Leumann - US Patent 5,319,080, 1994 - Google Patents
The invention relates to nucleosides having a bicy cloS, 3, 0-8-oxaoctane skeleton, to a
process for their preparation by substituting an anomeric leaving group by a nuclein base …
process for their preparation by substituting an anomeric leaving group by a nuclein base …
Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates
KH Altmann, R Imwinkelried, A Eschenmoser - US Patent 5,700,920, 1997 - Google Patents
OR; in which A is—CH;---or—CH2CH2—. R1 is hydrogen or a protective group. R2 is
hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide …
hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide …
Backbone modified oligonucleotide analogues
PD Cook, YS Sanghvi, JJ Vasseur, F Debart - US Patent 5,965,721, 1999 - Google Patents
Therapeutic oligonucleotide analogues which have improved nuclease resistance and
improved cellular uptake are provided. Replacement of the normal phosphorodiester inter …
improved cellular uptake are provided. Replacement of the normal phosphorodiester inter …
Backbone modified oligonucleotide analogues
PD Cook, YS Sanghvi, JJ Vasseur, F Debart - US Patent 5,610,289, 1997 - Google Patents
Therapeutic oligonucleotide analogues which have improved nuclease resistance and
improved cellular uptake are provided. Replacement of the normal phosphorodiester inter …
improved cellular uptake are provided. Replacement of the normal phosphorodiester inter …
Nucleoside 5'-monophosphate mimics and their prodrugs
P Cook, G Wang, T Bruice, V Rajappan… - US Patent App. 10 …, 2004 - Google Patents
The present invention relates to novel nucleoside 5'-mono phosphate mimics, which contain
novel nucleoside bases and phosphate moiety mimics optionally having Sugar …
novel nucleoside bases and phosphate moiety mimics optionally having Sugar …
2'Modified nucleoside and nucleotide compounds
CA Buhr, M Matteucci - US Patent 5,466,786, 1995 - Google Patents
US5466786A - 2'modified nucleoside and nucleotide compounds - Google Patents
US5466786A - 2'modified nucleoside and nucleotide compounds - Google Patents 2'modified …
US5466786A - 2'modified nucleoside and nucleotide compounds - Google Patents 2'modified …
Acyclic nucleoside analogs and oligonucleotide sequences containing them
PD Cook, DJ Delecki, C Guinosso - US Patent 5,576,427, 1996 - Google Patents
US5576427A - Acyclic nucleoside analogs and oligonucleotide sequences containing them -
Google Patents US5576427A - Acyclic nucleoside analogs and oligonucleotide sequences …
Google Patents US5576427A - Acyclic nucleoside analogs and oligonucleotide sequences …
Tricyclic nucleosides or nucleotides as therapeutic agents
PD Cook, Y Jin, J Lambert, M Prhavc… - US Patent …, 2007 - Google Patents
US7268119B2 - Tricyclic nucleosides or nucleotides as therapeutic agents - Google Patents
US7268119B2 - Tricyclic nucleosides or nucleotides as therapeutic agents - Google Patents …
US7268119B2 - Tricyclic nucleosides or nucleotides as therapeutic agents - Google Patents …