Social anxiety disorder-associated gut microbiota increases social fear

NL Ritz, M Brocka, MI Butler… - Proceedings of the …, 2024 - National Acad Sciences
Social anxiety disorder (SAD) is a crippling psychiatric disorder characterized by intense
fear or anxiety in social situations and their avoidance. However, the underlying biology of …

Gut microbiota regulates key modulators of social behavior

A Parashar, M Udayabanu - European Neuropsychopharmacology, 2016 - Elsevier
Social behavior plays a pivotal role in the mental well-being of an individual. Continuous
efforts in the past have led to advancements in the area of how the brain regulates emotion …

[HTML][HTML] The gut microbiome in social anxiety disorder: evidence of altered composition and function

MI Butler, TFS Bastiaanssen, C Long-Smith… - Translational …, 2023 - nature.com
The microbiome-gut-brain axis plays a role in anxiety, the stress response and social
development, and is of growing interest in neuropsychiatric conditions. The gut microbiota …

[HTML][HTML] Ingestion of probiotic (Lactobacillus helveticus and Bifidobacterium longum) alters intestinal microbial structure and behavioral expression following social …

KA Partrick, AM Rosenhauer, J Auger, AR Arnold… - Scientific Reports, 2021 - nature.com
Social stress exacerbates anxious and depressive behaviors in humans. Similarly, anxiety-
and depressive-like behaviors are triggered by social stress in a variety of non-human …

[HTML][HTML] Brain neurotransmitter modulation by gut microbiota in anxiety and depression

F Huang, X Wu - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Anxiety and depression are highly prevalent mental illnesses worldwide and have long
been thought to be closely associated to neurotransmitter modulation. There is growing …

[HTML][HTML] Experiencing social exclusion changes gut microbiota composition

CS Kim, GE Shin, Y Cheong, JH Shin, DM Shin… - Translational …, 2022 - nature.com
Gut microbiota is suggested to regulate the host's mental health via the gut-brain axis. In this
study, we investigated the relationship between the microbiome and psychological pain due …

[HTML][HTML] Effects of regulating intestinal microbiota on anxiety symptoms: a systematic review

B Yang, J Wei, P Ju, J Chen - General psychiatry, 2019 - ncbi.nlm.nih.gov
Background Anxiety symptoms are common in mental diseases and a variety of physical
disorders, especially in disorders related to stress. More and more basic studies have …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

[HTML][HTML] Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress

A Bharwani, MF Mian, MG Surette, J Bienenstock… - BMC medicine, 2017 - Springer
Background Stress-related disorders involve systemic alterations, including disruption of the
intestinal microbial community. Given the putative connections between the microbiota …

Updated review of research on the gut microbiota and their relation to depression in animals and human beings

Z Yang, J Li, X Gui, X Shi, Z Bao, H Han, MD Li - Molecular psychiatry, 2020 - nature.com
The gut microbiota are being called the human “second brain,” as they play a key role in the
regulation of the central nervous system (CNS). Recent findings provide strong evidence for …