Mitochondria play a critical role in several metabolic processes and apoptotic pathways,
regulating life cycle from the cradle to the grave. Despite the evidence of morphological …

Mitochondria are involved in ATP supply to cells through oxidative phosphorylation
(OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in …

Many lines of evidence suggest that mitochondria have a central role in ageing-related
neurodegenerative diseases. However, despite the evidence of morphological, biochemical …

Mitochondria are implicated in several metabolic pathways including cell respiratory
processes, apoptosis, and free radical production. Mitochondrial abnormalities have been …

Age is the main risk factor for a number of human diseases, including neurodegenerative
disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral …

Mitochondrial dysfunctions are supposed to be responsible for many neurodegenerative
diseases dominating in Alzheimer's disease (AD), Parkinson's disease (PD), and …

Mitochondria are crucial regulators of energy metabolism and apoptotic pathways and have
been closely linked to the pathogenesis of neurodegenerative disorders. In this review we …

Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

Mitochondria play a critical role in neuron viability or death as it regulates energy
metabolism and cell death pathways. They are essential for cellular energy metabolism …

Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of people
worldwide. Currently, there is no effective treatment for AD, which indicates the necessity to …